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Ultrasound, Doppler and other signs during drug-free transition from subclinical hypothyroidism to euthyroidism: a case report.
AME Case Rep
January 2025
Ushakov Thyroid Clinic, Moscow, Russia.
Background: It is known that subclinical hypothyroidism (SCH) often converts to euthyroidism. However, the mechanism of such changes is unclear and can only be speculated. This difficulty is likely due to limitations in diagnostic guidelines and their interpretation.
View Article and Find Full Text PDFAssociation of Myasthenia Gravis With Autoimmune Thyroid Disease: A Bidirectional Mendelian Randomization Study.
Brain Behav
January 2025
Department of Neurology, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
Background And Purpose: Observational studies have indicated a high occurrence of coexistence between myasthenia gravis (MG) and autoimmune thyroid disease (AITD) in clinical settings, but the causal relationship between the two conditions remains ambiguous. Therefore, this study endeavors to investigate the causal links between MG, along with its subgroups, and AITD through a Mendelian randomization (MR) approach.
Methods: Genetic instrumental variables associated with MG and AITD were selected from three major publicly available GWAS databases for MR analysis.
Unresolved Complete Heart Block in a Patient Treated for Euthyroid Graves' Disease: A Diagnostic Dilemma.
Cureus
December 2024
Diabetes and Endocrinology, United Lincolnshire Hospital NHS Trust, Lincoln, GBR.
The cardiovascular implications of thyroid disease have been recognized as one of the most characteristic signs that result from the effect of thyroid hormone (TH). Both hyperthyroidism and hypothyroidism produce changes in cardiac contractility, myocardial oxygen consumption, cardiac output, blood pressure, and systemic vascular resistance. The bradyarrhythmias, including atrioventricular block and sick sinus syndrome, are exceedingly rare in hyperthyroidism.
View Article and Find Full Text PDFThe Impact of Maternal Graves' Disease on Neonatal Thyroid Function: A Systematic Review.
Cureus
December 2024
Department of Midwifery, School of Health and Care Sciences, University of West Attica, Athens, GRC.
Maternal Graves' disease (GD) poses a significant risk to neonatal thyroid function due to the transplacental transfer of thyrotropin receptor antibodies (TRAbs). This systematic review aims to assess the impact of maternal GD on neonatal thyroid outcomes and identify key maternal factors influencing these outcomes. A comprehensive literature search was conducted across PubMed, Scopus, and Cochrane, resulting in the inclusion of 18 studies published from 2014 to 2024.
View Article and Find Full Text PDFA Two-Way Mendelian Randomization Analysis on the Link between Thyroid Activity Function and Coronary Atherosclerosis.
Rev Cardiovasc Med
December 2024
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, China.
Article Synopsis
- The study investigates how thyroid hormones may contribute to coronary atherosclerosis, a leading cause of coronary artery disease (CAD).
- Utilizing large genetic databases, the research examines various thyroid-related disorders and their potential links to coronary atherosclerosis through Mendelian Randomization techniques.
- Results indicate that conditions like hypothyroidism and Graves' disease increase the risk of coronary atherosclerosis, while no causal relationship was found between certain thyroid hormones (FT4 and TSH) and the disease.
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