Enteric fever (formerly typhoid fever) is a bacterial illness caused by fecal-oral transmission of or . In early 2018, an outbreak of resistant to third-generation cephalosporins, ampicillin, ciprofloxacin, trimethroprim-sulfamethoxazole, and chloramphenicol was reported in Pakistan. This strain, termed "extensively resistant typhi," has infected more than 5000 patients in endemic areas of South Asia, as well as travelers to and from these areas, including 5 cases in the United States. We present the case of one such child who developed extensively resistant enteric fever during a recent visit to Pakistan and required broader antimicrobial treatment than typically required. Clinicians should be aware that incoming cases of enteric fever may be nonsusceptible to commonly recommended antibiotics and that extensively resistant requires treatment with carbapenems such as meropenem or azithromycin.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/0009922819881203 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effects of probiotic therapy combined with personalized nursing on immune function and nursing compliance in children with acute gastroenteritis.
Afr J Reprod Health
November 2024
Department of Neonatology, The First Hospital of China Medical University, Shenyang, 110002, Liaoning, China.
This was an original study that mainly explored the effect of probiotic therapy and personalized nursing on immune function in children with acute gastroenteritis. One hundred and twelve (112) children with acute gastroenteritis were selected and divided into an intervention group and a control group. The control group accepted omeprazole enteric-coated capsules and routine nursing.
View Article and Find Full Text PDFContext: Anemia is a medical condition resulting from a reduction in the number of red blood cells below the reference range. It is a major public health problem, particularly among adolescents, as it can have negative effects on cognitive performance, growth and reproduction. This study aims to assess the determinants of anemia among adolescents in schools in the city of Douala.
View Article and Find Full Text PDFA core glycolipid vaccine elicits cross-reactive antibodies against Salmonella spp. and protects against invasive nontyphoidal Salmonella disease in mice.
J Infect Dis
December 2024
Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Background: Enteric fever caused by Salmonella enterica serovars Typhi and Paratyphi A in addition to gastroenteritis and invasive disease, predominantly attributable to nontyphoidal Salmonella serovars Typhimurium and Enteritidis, are major causes of death and disability across the globe. A broad-spectrum vaccine that protects against disease caused by typhoidal and nontyphoidal serovars of Salmonella is not available for humans but would prevent a considerable burden of disease worldwide.
Methods: We previously developed a broad-spectrum vaccine for Gram-negative bacteria that is based on the inner core domain of detoxified Escherichia coli O111, Rc (J5) mutant lipooligosaccharide, a highly conserved antigen across Gram-negative bacteria, complexed with an outer membrane protein of group B Neisseria meningitidis.
Vi capsular polysaccharide of Salmonella enterica serovar Typhi disturbs autophagy to increase intracellular survival in macrophages.
Microb Pathog
December 2024
Department of Laboratory Medicine, Affiliated Hospital, Jiangsu University, Zhenjiang, Jiangsu 212001, China. Electronic address:
The autophagy pathway plays a crucial role in resistance to bacterial infection in the host. Salmonella enterica serovar Typhi (S. Typhi), a human restricted pathogen, causes a systemic infection known as typhoid fever.
View Article and Find Full Text PDFFunctional role of the biofilm regulator CsgD in sv. Typhi.
Front Cell Infect Microbiol
December 2024
Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.
Introduction: Typhoid fever is an infectious disease primarily caused by sv. Typhi ( Typhi), a bacterium that causes as many as 20 million infections and 600,000 deaths annually. Asymptomatic chronic carriers of S.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!