Objective: Newborns exposed to drugs in utero are at risk of developing neonatal abstinence syndrome (NAS), characterized by behavioral changes and physiologic instability. Finnegan scoring tool quantifies severity of symptoms and guides treatment. This article evaluates whether time of day and the number of shift hours affects modified Finnegan scores, and the subjective component of these scores.
Study Design: Institutional review board-approved, retrospective chart review of newborns admitted to neonatal intensive care or transitional nursery from 2011 to 2014.
Inclusion Criteria: > 35 weeks' gestation, known maternal substance use, positive maternal or newborn urine, or meconium drug screen, NAS treatment.
Results: A total of 101 charts were evaluated. Mean treatment duration was 31.8 days (standard deviation ±18.3). There was no significant relationship between observer shift hour and high scores (> 8) ( = 0.83). Highest scores occurred in the afternoon, decreased at night ( = 0.03), and throughout admission ( < 0.0001). Weekend and weekday scores were similar ( = 0.4). The objective component of the scores remained similar throughout the day ( = 0.91) and week ( = 0.52).
Conclusion: Finnegan scores given by nurses were not influenced by shift hour. Time of day did not influence overall high scores or the proportion of objective to total Finnegan score. Inter-rater reliability was maintained regardless of time of day or day of the week.
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http://dx.doi.org/10.1055/s-0039-1698458 | DOI Listing |
Eur J Neurosci
January 2025
Translational Neuromodeling Unit, University of Zurich and ETH Zurich, Zurich, Switzerland.
Anxiety is one of the most common and debilitating mental health disorders, and is related to changes in interoception (perception of bodily states). While anxiety is more prevalent in women than men, gender differences in interoception-anxiety associations are often overlooked. Here, we examined gender-specific relationships between anxiety and interoception in the breathing domain, utilising multicentre data pooled from four study sites (N = 175; 51% women).
View Article and Find Full Text PDFSemin Perinatol
December 2024
Yale School of Medicine, New Haven, CT, USA.
Increased incidence of Neonatal Opioid Withdrawal Syndrome has prompted innovation in assessment and management approaches. The Finnegan Approach and the Eat, Sleep, Console are the two most commonly described approaches, though they differ substantially. The goals of this review article are to describe and compare these approaches and published outcomes, including areas of uncertainty that may inform future directions.
View Article and Find Full Text PDFAdv Neonatal Care
December 2024
Author Affiliations: Nationwide Children's Hospital, Columbus, Ohio(Drs Kelly and Bagwell); OhioHealth Grant Medical Center(Dr Kelly); and University of South Alabama(Drs Kelly and Coates-Huffman).
Background: In 2020, the rate of newborns diagnosed with neonatal abstinence syndrome (NAS) in the United States was 6.3 for every 1000 newborn hospitalizations. Resources used to care for this population, particularly NICU beds, are being overwhelmed.
View Article and Find Full Text PDFClin Pharmacol Ther
November 2024
St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
The No-POPPY study (NCT03396588), a double-blind, randomized trial compared morphine with clonidine therapy for neonatal opioid withdrawal syndrome (NOWS) and found that the duration of treatment was similar across groups. This is significant because perinatal use of morphine has the potential for neurodevelopmental consequences. Still, the clonidine group reached symptom stabilization (Finnegan score (FS) < 8) later than the morphine group and had a more significant number of patients who required adjunct therapy.
View Article and Find Full Text PDFSleep
November 2024
Department of Exercise Science, University of South Carolina, Columbia, South Carolina, USA.
Study Objectives: Evaluate the performance of actigraphy-based open-source and proprietary sleep algorithms compared to polysomnography in children with suspected sleep disorders.
Methods: In a sleep clinic, 110 children (5-12 years, 54% female, 50% Black, 82% with sleep disorders) wore wrist-placed ActiGraph GT9X during overnight polysomnography. Actigraphy data were scored as sleep or wake using open-source GGIR and proprietary ActiLife software.
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