Chemometrics offers an important complementary tool to enhance the searching and isolation of bioactive natural products from natural sources.
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http://dx.doi.org/10.1016/j.drudis.2019.09.016 | DOI Listing |
Handb Clin Neurol
March 2025
Department of Psychology, University of Campania 'Luigi Vanvitelli', Caserta, Italy. Electronic address:
This chapter deals with the unique human abilities of using tools, imitating others' gestures, drawing, and building complex items. Herein, after a brief overview of clinical manifestations and assessment of disorders of tool use and imitation (upper limb apraxia) and of the impairments in drawing and assembling multipart objects (constructional apraxia), brain asymmetries are discussed mainly starting from the neuropsychologic studies on patients with focal brain lesions, although both upper limb apraxia and constructional apraxia are often observed during the course of neurodegenerative diseases. Although no room is allowed here for a full discussion of brain-behavior relationships, relevant functional neuroimaging findings in healthy individuals are considered.
View Article and Find Full Text PDFJ Am Chem Soc
March 2025
Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, United States.
Semiconductor devices often rely on high-purity materials and interfaces achieved through vapor- and vacuum-based fabrication methods, which can enable precise compositional control down to single atomic layers. Compared to groups IV and III-V semiconductors, hybrid perovskites (HPs) are an emergent class of semiconductor materials with remarkable solution processability and compositional variability that have facilitated rapid experimentation to achieve new properties and progress toward efficient devices, particularly for solar cells. Surprisingly, vapor deposition techniques for HPs are substantially less developed, despite the complementary benefits that have secured vapor methods as workhorse tools for semiconductor fabrication.
View Article and Find Full Text PDFFront Psychiatry
February 2025
Respiratory Failure Unit, G. Papanikolaou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Background: Adolescent smoking is a significant public health concern, as early nicotine addiction leads to more severe addiction and reduced cessation success during adulthood. While nicotine replacement therapy (NRT) is an effective smoking cessation tool in adults, its efficacy in adolescents is less clear.
Objective: This systematic review evaluates the effectiveness and safety of NRT for smoking cessation in adolescents.
Indian J Otolaryngol Head Neck Surg
February 2025
Department of Otorhinolaryngology and Head and Neck Surgery, Father Muller Medical College, Mangalore, India.
Simulation, in medical education has provided a novel way to impart education which will help students acquire the required skills to achieve their learning objectives. The aim of our study was to evaluate the performance of students exposed to otoscopy simulator-based learning versus traditional learning with observation and also to know the students' perceptions via a questionnaire at the end of the module. This was a prospective interventional study, conducted on third-year medical students, sixty in number, divided into two groups by the lottery method.
View Article and Find Full Text PDFFront Neurol
February 2025
Catholic Health Initiatives (CHI) Memorial Neuroscience Institute, Morehouse School of Medicine, Chattanooga, TN, United States.
Background: Stroke is the leading cause of adult disability worldwide, with approximately 30% of strokes remaining cryptogenic. One potential important etiology is a patent foramen ovale (PFO), which may contribute to stroke through paradoxical thromboembolism or thromboembolus formation. Recent advancements in robot-assisted transcranial Doppler (raTCD) have shown increased sensitivity in detecting right-to-left shunt (RLS) compared to transthoracic echocardiography (TTE), particularly in detecting the large shunts which are associated with higher stroke risk.
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