A Holistic Intervention for Oral Lichen Planus.

J Contemp Dent Pract

Department of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan, Kingdom of Saudi Arabia.

Published: July 2019

Oral lichen planus (OLP) is a chronic immune-mediated, inflammatory, and psychosomatic condition that frequently affects the oral mucosa in a typical bilateral pattern, often noticed in middle-aged females. It involves the buccal, lingual, and/or gingival mucosa and is also an oral potentially malignant disorder (OPMD). OLP is associated with etiological factors ranging from viruses like hepatitis C, systemic factors like thyroid disorders, local factors like dental plaque, calculus and cuspal trauma, to deep rooted, often underestimated, psychological triggers. OLP is routinely encountered in oral medicine clinics and is sometimes accompanied by the simultaneous involvement of skin, nails, genitals, and/or mucous membranes. Although OLP is multifactorial in origin, a large share of these presentations can be attributed chiefly to psychological factors like stress, anxiety, and depression. OLP is even more striking as its genesis, progression, and exacerbation closely mirror the dynamics of emotional disturbance.

Download full-text PDF

Source

Publication Analysis

Top Keywords

oral lichen
8
lichen planus
8
oral
5
olp
5
holistic intervention
4
intervention oral
4
planus oral
4
planus olp
4
olp chronic
4
chronic immune-mediated
4

Similar Publications

Lichen planus is a common mucocutaneous disorder that can affect various parts of the body, with its erosive variant typically involving the oral mucosa. This variant rarely affects the skin, and even less commonly, the flexural regions. Here, we present a case of a 14-year-old girl who presented with ulcerated, itchy lesions in the intertriginous areas for one year.

View Article and Find Full Text PDF

Aim: This study aimed to evaluate the effectiveness of fenugreek as an adjuvant in managing oral potentially malignant disorders (OPMDs), specifically leukoplakia, lichen planus, and oral submucous fibrosis (OSMF).

Materials And Methods: Twenty-one participants prediagnosed with OPMDs were randomly divided into a study group (SG) and a control group (CG), with 10 participants in SG and 11 in CG, respectively. The SG received 2 gm of fenugreek as an adjuvant with standard systemic treatments tailored to the respective lesions: intralesional injection of vitamin A 1,00,000 IU (Aquasol A) and topical application of triamcinolone acetonide 0.

View Article and Find Full Text PDF

Background/purpose: Oral lichen planus (OLP) is a chronic inflammatory disorder characterized by basement membrane disruption, which plays a crucial role in its pathogenesis. Matrix metalloproteinases (MMPs), a group of proteolytic enzymes, contribute to the degradation of the basement membrane. The specific MMPs secreted by keratinocytes in OLP lesions and relevant regulatory mechanisms are not fully understood.

View Article and Find Full Text PDF

Background/purpose: Oral leukoplakia (OLK) and oral lichen planus (OLP) represent two common oral potentially malignant disorders. It would be interesting to know scientific output and characteristics of studies on OLK and OLP.

Materials And Methods: This study aimed to investigate and compare scientometric characteristics of articles on OLK and OLP in the Scopus database, with emphasis on the analysis of the keywords that can reflect research directions and topics of concern.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!