Constituents from the Leaves of and Their Protective Activity in HEK 293t Cells Damaged by CdCl.

J Nat Prod

State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences , Inner Mongolia University, Hohhot , People's Republic of China 010070.

Published: October 2019

Maxim, a relict originating from the Tertiary Period, is an endemic species of Zygophyllaceae in China. Three new monoterpenoids (-), two new phenols (, ) with unusual -sulfoglucosyl groups, a new flavonoid (), and nine known compounds were isolated from the leaves of . The structures of these compounds were determined by interpretation of NMR, MS, and ECD data. Some of the isolated compounds showed protective effects on HEK 293t cells damaged by CdCl, with IC values being 55.7 and 80.3 μM for compounds and , respectively, at the time point of 48 h after treatment.

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http://dx.doi.org/10.1021/acs.jnatprod.9b00212DOI Listing

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