Integration of nursing classroom didactics with clinical and simulation experiences is crucial to obtaining improved student learning outcomes and successful academic achievement. According to the Institute of Medicine (2010), to ensure the delivery of safe, patient-centered care across settings, the nursing education system must be improved. Patient needs have become more complicated, and nurses need to attain requisite competencies to deliver high-quality care. An important aim is to increase active learning behaviors and maintain student engagement, which will foster an effort to learn and meet the complex needs of patients today. The integration of clinical and simulation with theory concepts can contribute to successful student development, confidence, self-efficacy, and reenforced desire to learn which is the key to success and competence development. Teamwork and collaboration are valued in nursing educational objectives as well as in the workplace. Blending a shared vision and mutual expectations helps to meet goals.
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http://dx.doi.org/10.1097/DCC.0000000000000385 | DOI Listing |
Oper Neurosurg (Hagerstown)
July 2024
Neurosurgical Simulation and Artificial Intelligence Learning Centre, Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal , Quebec , Canada.
Background And Objectives: Subpial corticectomy involving complete lesion resection while preserving pial membranes and avoiding injury to adjacent normal tissues is an essential bimanual task necessary for neurosurgical trainees to master. We sought to develop an ex vivo calf brain corticectomy simulation model with continuous assessment of surgical instrument movement during the simulation. A case series study of skilled participants was performed to assess face and content validity to gain insights into the utility of this training platform, along with determining if skilled and less skilled participants had statistical differences in validity assessment.
View Article and Find Full Text PDFJAMA
January 2025
Department of Emergency Medicine, Henry Ford Health, Detroit, Michigan.
Importance: The emergency department (ED) offers an opportunity to initiate palliative care for older adults with serious, life-limiting illness.
Objective: To assess the effect of a multicomponent intervention to initiate palliative care in the ED on hospital admission, subsequent health care use, and survival in older adults with serious, life-limiting illness.
Design, Setting, And Participants: Cluster randomized, stepped-wedge, clinical trial including patients aged 66 years or older who visited 1 of 29 EDs across the US between May 1, 2018, and December 31, 2022, had 12 months of prior Medicare enrollment, and a Gagne comorbidity score greater than 6, representing a risk of short-term mortality greater than 30%.
Mol Biotechnol
January 2025
Enzyme and Microbial Research Center, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Glucanases are widely applied in industrial applications such as brewing, biomass conversion, food, and animal feed. Glucanases catalyze the hydrolysis of glucan to produce the sugar hemiacetal through hydrolytic cleavage of glycosidic bonds. Current study aimed to investigate structural insights of a glucanase from Clostridium perfringens through blind molecular docking, site-specific molecular docking, molecular dynamics (MD) simulation, and binding energy calculation.
View Article and Find Full Text PDFRadiol Phys Technol
January 2025
Department of Radiotherapy, Sri Shankara Cancer Hospital and Research Centre, 1st Cross, Shankarapuram, Basavanagui, Bengaluru, 560004, Karnataka, India.
This study evaluates the dosimetric impact of arc simulation angular resolution in VMAT-based Single Isocentre Multiple Target (SIMT) SRS, focusing on their dependence on target size, isocentre distance, number of arcs, and arc type. A phantom study analysed angular resolution (0.5°, 1°, 2°) effects on dosimetric accuracy for PTVs of 0.
View Article and Find Full Text PDFMol Biol Rep
January 2025
Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, India.
Background: Exosomes are extracellular vesicles released by cells that mediate intercellular communication and actively participate in cancer progression, metastasis, and regulation of immune response within the tumour microenvironment. Inhibiting exosome release from cancer cells could be employed as a therapeutic against cancer.
Methods And Results: In the present study, we have studied the effects of Acorus calamus in inhibiting exosome secretion via targetting Rab27a and neutral sphingomyelinase 2 (nSMase2) in HER2-positive (MDA-MB-453), hormone receptor-positive (MCF-7) and triple-negative breast cancer (MDA-MB-231) cells.
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