Silver-mediated intramolecular α-C(sp)-H bond functionalization of the methylthio group has been established in the presence of Selectfluor as an additive. This novel strategy provides efficient access to various diverse sulfur-based heterocycles with good yields and functional group compatibility. It is noteworthy that the completely novel benzooxathiin-4-imine skeletons were reported for the first time in this study.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.joc.9b02202 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Silver-Promoted Site-Selective Intramolecular Cyclization of 2-Methylthiobenzamide Through α-C(sp)-H Functionalization.
J Org Chem
November 2019
Department of Chemistry and Chemical Biology , Indiana University Purdue University Indianapolis, Indianapolis , Indiana 46202 , United States.
Silver-mediated intramolecular α-C(sp)-H bond functionalization of the methylthio group has been established in the presence of Selectfluor as an additive. This novel strategy provides efficient access to various diverse sulfur-based heterocycles with good yields and functional group compatibility. It is noteworthy that the completely novel benzooxathiin-4-imine skeletons were reported for the first time in this study.
View Article and Find Full Text PDFLigand-controlled, tunable silver-catalyzed C-H amination.
J Am Chem Soc
December 2014
Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.
The development of readily tunable and regioselective C-H functionalization reactions that operate solely through catalyst control remains a challenge in modern organic synthesis. Herein, we report that simple silver catalysts supported by common nitrogenated ligands can be used to tune a nitrene transfer reaction between two different types of C-H bonds. The results reported herein represent the first example of ligand-controlled and site-selective silver-promoted C-H amination.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!