Purpose: The purpose of this study was to present a new absorbable spacer for medial compartmental knee osteoarthritis (OA). The functional and radiographic results of patients treated with the novel surgical technique were also evaluated to investigate its clinical feasibility.
Methods: Patients with medial compartmental knee OA who underwent open-wedge high tibial osteotomy (HTO) with absorbable β-TCP/PLGA [30% beta-tricalcium phosphate and 70% poly (lactic-co-glycolic acid)] spacer implantation and proximal fibular osteotomy from January 2016 to February 2017 were retrospectively analyzed. The operation time, blood loss, and relevant complications were reviewed. The femorotibial angle (FTA), varus angle (VA), joint line convergence angle (JLCA), American Knee Society Score (KSS), and visual analog scale (VAS) score were recorded preoperatively and at the final follow-up, respectively.
Results: At the final follow-up, the mean FTA and JLCA were 179.85° ± 4.34° and 2.44° ± 1.26°, respectively, which were smaller than the preoperative values (182.94° ± 3.86° and 4.12° ± 1.65°, respectively; both < 0.001). The final VA and VAS score were lower than those measured preoperatively (both < 0.001). The clinical and functional KSSs at the final follow-up were higher than the preoperative scores ( < 0.001).
Conclusions: This novel absorbable spacer could provide adequate stability for the tibial osteotomy gap, at a lower cost than a traditional plate. With the use of this spacer as an osteoinductive and biodegradable device, secondary surgery for fixation removal could be avoided. The novel surgical technique could improve both the radiographic appearance and the function of the knee in patients with knee OA.
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http://dx.doi.org/10.1080/08941939.2019.1670296 | DOI Listing |
BMC Musculoskelet Disord
January 2025
Senior Department of Orthopedics, The Fourth Medical Center of PLA General Hospital, No. 51 Fucheng Road, Beijing, 100048, People's Republic of China.
Background: In medial mobile-bearing unicompartmental knee arthroplasty (MB-UKA), the position of the bearing does not correspond to the planned position which will increasing the risk of bearing dislocation. This study aimed to explore the relationship between the malposition of the femoral and tibial components and the phenomenon of bearing deviation using postoperative radiological measurements.
Methods: One hundred twenty patients who underwent mobile-bearing uni-compartmental knee arthroplasty (MB-UKA) at our hospital between January and August 2023 were enrolled in this retrospective study.
Acta Orthop
January 2025
Department of Orthopaedics and Sports Medicine, Erasmus MC University Medical Centre Rotterdam; Department of General Practice, Erasmus MC University Medical Centre, Rotterdam, the Netherlands.
Background And Purpose: For medial knee osteoarthritis (OA), operative and nonoperative treatment options are available. Two widely applied unloading therapies are a valgus unloader brace and a high tibial osteotomy (HTO). We aimed to compare the effects of a valgus unloader knee brace with an HTO on knee pain after 1 year in patients with symptomatic medial knee OA.
View Article and Find Full Text PDFDiagnostics (Basel)
January 2025
Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Bei-Hu Branch, Taipei 10845, Taiwan.
A 66-year-old woman presented with persistent knee effusion three months after undergoing a cemented medial uni-compartmental knee replacement. She was afebrile and able to walk with a stick. Physical examination revealed moderate effusion.
View Article and Find Full Text PDFBone Jt Open
December 2024
St John of God Healthcare, Perth, Australia.
Aims: Unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) have both been shown to be effective treatments for osteoarthritis (OA) of the knee. Many studies have compared the outcomes of the two treatments, but less so with the use of robotics, or individualized TKA alignment techniques. Functional alignment (FA) is a novel technique for performing a TKA and shares many principles with UKA.
View Article and Find Full Text PDFDev Cell
December 2024
Department of Neurobiology, University of Utah, Salt Lake City, UT, USA. Electronic address:
The apical extracellular matrix (aECM), organized by polarized epithelial cells, exhibits complex structures. The tectorial membrane (TM), an aECM in the cochlea mediating auditory transduction, exhibits highly ordered domain-specific architecture. α-Tectorin (TECTA), a glycosylphosphatidylinositol (GPI)-anchored ECM protein, is essential for TM organization.
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