A chemoenzymatic method for the halocyclization of unsaturated alcohols and acids by using the robust V-dependent chloroperoxidase from Curvularia inaequalis (CiVCPO) as catalyst has been developed for the in situ generation of hypohalites. A broad range of halolactones and cyclic haloethers are formed with excellent performance of the biocatalyst.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973245PMC
http://dx.doi.org/10.1002/cssc.201902240DOI Listing

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