Objective: Recognizing frailty, also known as clinical geriatric syndrome in the elderly that is characterized by high vulnerability and low resilience, and its extensive influence in clinical practice is challenging. This study aims to develop a social frailty prediction system based on machine learning approaches in order to identify the social frailty status of the elders in order to advance appropriate social services provision.
Materials And Methods: This cross-sectional study enrolled and collected information from 595 community-dwelling seniors aged 65+. Fourteen predictors established from questionnaires and electronic medical records were used to predict the social frailty of participants. Bagged classification and regression trees, model average neural network, random forest, C5.0, eXtreme gradient boosting, and stochastic gradient boosting were used to build the predictive model in use. Performance was compared using accuracy, kappa, area under receiver operating characteristic curve, sensitivity, and specificity. The frailty predictive system was web-based and built upon representational state transfer application program interfaces.
Results: C5.0 achieved the best overall performance than remaining learners, and was adopted as the base learner for the social frailty prediction system. In terms of the area under receiver operating characteristic curve (AUC), health literacy (AUC = 0.68) was found to be the most important variable for predicting one's social frailty, followed by comorbidity (AUC = 0.67), religious participation (AUC = 0.67), physical activity (AUC = 0.66), and geriatric depression score (AUC = 0.62).
Conclusions: Results suggest that a combination of such data that is both available and unavailable from electronic medical records is predictive of the social frailty of an elderly population.
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http://dx.doi.org/10.1016/j.ijmedinf.2019.103979 | DOI Listing |
Clin Interv Aging
January 2025
Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou, People's Republic of China.
Objective: To understand the current status and analyse the factors influencing frailty in older adults patients with pulmonary tuberculosis.
Methods: This retrospective case-control study included 204 older adults patients with pulmonary tuberculosis. The enrolled patients were divided into a frailty group (n = 101) and a non-frailty group (n = 103).
J Affect Disord
January 2025
Department of Neurology & Innovation Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, China; National Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, China; Neurodegenerative Laboratory of Ministry of Education of the People's Republic of China, Beijing, China. Electronic address:
Background: Frailty and social contact are significant factors influencing dementia risk. While previous studies have separately examined these factors, their combined impact on dementia remains underexplored.
Methods: This study included 338,567 UK biobank participants from 2006 to 2010, with follow-up until December 2022.
J Frailty Aging
February 2025
Division of Geriatrics and Osher Center for Integrative Health, University of California, San Francisco, San Francisco, CA, USA.
Background: Pre-frailty is highly prevalent and multimodal lifestyle interventions are effective for preventing transition to frailty. However, little is known about the potential for medical group visits (MGV) to prevent frailty progression.
Objectives: To assess the feasibility and acceptability of the MGV Age Self Care-Resilience.
J Frailty Aging
February 2025
Department of Human Neuroscience, Sapienza University, Rome, Italy; National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy; Aging Research Center, Department of Neurobiology, Care Sciences, and Society, Karolinska Institute and Stockholm University, Stockholm, Sweden.
The International Conference on Frailty and Sarcopenia Research (ICFSR) Task Force convened in March 2024 to address patient-reported outcomes measures (PROMs) in the field of sarcopenia. PROMs are crucial to enhance healthcare services at both individual and societal levels. PROMs complement objective outcome measures by capturing insights that patients are best suited to judge.
View Article and Find Full Text PDFJ Frailty Aging
February 2025
Department of Brain Sciences, Imperial College London, UK. Electronic address:
Purpose: Concerns about falling (CaF) are common in older adults. They are associated with increased risk of falls, activity restriction, social isolation, and physical deconditioning. This systematic review assessed if frailty is a risk factor for CaF.
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