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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955080 | PMC |
| http://dx.doi.org/10.14744/AnatolJCardiol.2019.78546 | DOI Listing |
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Cangrelor Use for Viabahn Stent Graft Patency as Bridge to Coronary Artery Bypass Graft Surgery.
J Pharm Pract
January 2025
Department of Cardiothoracic Surgery, Jefferson Health Abington Hospital, Abington, PA, USA.
Article Synopsis
- Utilization of cangrelor as a bridging therapy to cardiac surgery has been noted for stent placement, but less so for endovascular revascularization.
- The case involves a 47-year-old female with a significant arterial dissection requiring a Viabahn endoprosthesis and subsequent cardiac procedures.
- A combination of cangrelor, aspirin, and bivalirudin was employed to manage the patient’s coronary disease and ensure the effectiveness of the surgical intervention, showcasing a multi-disciplinary approach in complex cases.
The Use of Cangrelor in Cardiogenic Shock: Insights from the CAMEO Registry.
J Card Fail
October 2024
Henry Ford Health, Detroit, MI.
Article Synopsis
- The study investigates the use of cangrelor in patients with myocardial infarction (MI) who also have cardiogenic shock (CS), focusing on the infusion duration and transition to oral medications.
- A total of 249 patients with CS were analyzed, with significant observations on demographics, infusion times, and the occurrence of major adverse cardiovascular events (MACEs) and bleeding risks.
- The findings showed that patients with CS had longer cangrelor infusions compared to others, and that the use of mechanical circulatory support (MCS) was linked to longer infusion times and an increased risk of bleeding.
Strategies to optimize initial P2Y inhibitor therapy in STEMI patients.
Cardiovasc Revasc Med
September 2024
University of New Mexico, Division of Cardiology, Albuquerque, NM, USA. Electronic address:
Introduction: Dual antiplatelet therapy (DAPT) with aspirin and a P2Y inhibitor is the standard of care for patients who undergo percutaneous coronary intervention (PCI) for ST elevation myocardial infarction (STEMI). Though this regimen reduces rates of ischemic events in patients with STEMI, the optimal strategy for P2Y administration in STEMI patients is still evolving.
Purpose: The purpose of this review is to summarize current evidence on optimal use of ticagrelor and prasugrel in the acute phase of STEMI.
The Use of Cangrelor as Bridge Antiplatelet Therapy in a Patient with Recent Percutaneous Coronary Intervention for Acute Coronary Syndrome, Who Developed Esophageal Perforation After Transesophageal Echocardiography.
Turk Kardiyol Dern Ars
July 2024
Department of Cardiology, Kocaeli University Medical Faculty, Kocaeli, Türkiye.
Article Synopsis
- Dual antiplatelet therapy (DAPT) is crucial for managing patients with coronary artery disease during procedures like percutaneous coronary intervention (PCI), but can pose risks if surgery is needed urgently.
- Cangrelor, an intravenous medication, allows rapid and potent platelet inhibition, which can be quickly reversed, making it a potential solution for patients needing to temporarily stop DAPT.
- In a case of a patient with recent PCI who developed an esophageal perforation, prolonged cangrelor use effectively helped manage the situation without causing any thrombotic or bleeding complications.
The use of cangrelor in a complex vascular patient: A case report.
J Vasc Nurs
June 2024
Surgical Intensive Care Unit, University of Maryland Medical Center, 22 S. Greene Street, Baltimore, MD 21201, USA. Electronic address:
Article Synopsis
- Medical decision-making for high-risk surgeries involves careful evaluation of risks vs. benefits, especially regarding concurrent medications.
- Managing cardiovascular risks is crucial for patients having non-cardiac surgeries to ensure safe outcomes.
- The case study discusses how Cangrelor, a short-acting antiplatelet medication, was effectively used as a bridge for a patient needing dual antiplatelet therapy and urgent surgical intervention, potentially improving patient results.
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