AI Article Synopsis
- A new saponin has been identified from the methanol extract of plant roots, along with five previously known compounds.
- The extraction process involved multiple open column chromatography methods and various spectroscopic and spectrometric analyses.
- The novel saponin showed significant antibacterial activity against eleven Gram-negative bacteria, including multi-drug resistant strains, with minimum inhibitory concentration (MIC) values between 16 to 128 μg/mL.
Article Abstract
An unprecedented saponin is being reported herein together with five known compounds from the methanol extract of the roots of . The metabolites were obtained over repeated open column chromatography methods and spectroscopic followed by spectrometric techniques. The isolated compounds were tested against eleven Gram-negative bacteria including multidrug resistant strains. The results revealed considerable inhibition of the new saponin against the studied bacteria with MIC values ranging from 16 to 128 μg/mL.
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| http://dx.doi.org/10.1080/14786419.2019.1672689 | DOI Listing |
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