A new labdane-type diterpenoid, named vitexnegundin (), along with seven known compounds, including vitexilactone (), vitetrifolin D (), 13-hydroxy-5(10),14-halimadien-6-one (), (rel 3,5,8,9,10)-3,9-dihydroxy-13(14)-labden-16,15-olide (), artemetin (), vitexcarpin () and penduletin (), were isolated from the leaves of L. Their structures were elucidated by using spectroscopic methods, X-ray crystallographic analysis and comparison with those reported in the literature. Moreover, all isolated compounds were evaluated for their antimicrobial activity against ESBL-producing strain and methicillin-resistant .
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