Here we show that mouse IgG2a and IgG1 antibodies specific for the commensal cross-react with pathogen serotypes 2 and 4, although the cross-reactivity conferred by IgG2a is stronger than that by IgG1 antibodies. These findings may be important for understanding the -induced IgG isotype responses and have consequences for the development of an effective pneumococcal vaccine.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754875 | PMC |
| http://dx.doi.org/10.1155/2019/7906724 | DOI Listing |
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