AI Article Synopsis
- Primary retroperitoneal mucinous cystadenomas (PRMC) are uncommon benign tumors, with only 55 known cases in medical literature.
- A 19-year-old female diagnosed with hirsutism had a cystic mass in her left retroperitoneum, leading to high levels of dehydroepiandrosterone sulfate (DHEA-S) before surgery.
- After laparoscopic removal of the cyst, it was confirmed as PRMC, and while DHEA-S levels returned to normal post-surgery, there was no immediate improvement in hirsutism symptoms; this case uniquely ties PRMC to elevated androgen levels.
Article Abstract
Primary retroperitoneal mucinous cystadenomas (PRMC) are rare benign neoplasms with only 55 documented cases in the English literature so far. A 19-year-old female exhibited hirsutism and was found to have a cystic mass measuring 5.8 cm × 3.9 cm × 5.8 cm in the left retroperitoneum. During subsequent work up, a high pre-operative value of dehydroepiandrosterone sulfate (DHEA-S) was noted. The patient was referred to surgical oncology and underwent an uneventful laparoscopic cystectomy. Pathology classified the cyst as PRMC. Post-operatively, the patient's DHEA-S levels normalized, though there was no appreciable decrease in the patient's hirsutism in the short-term follow-up. The origin of PRMC is uncertain. Due to their unknown biological potential, surgical resection is usually recommended. To the best of our knowledge, this is the first report documenting a PRMC and elevated levels of androgens in conjunction with hirsutism.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153794 | PMC |
| http://dx.doi.org/10.3121/cmr.2019.1488 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pseudomyxoma retroperitonei secondary to appendiceal mucinous adenocarcinoma disguised as psoas abscess - A case report.
Int J Surg Case Rep
January 2025
Department of Surgery, Aga Khan University Hospital, Stadium Road, Karachi 74800, Pakistan. Electronic address:
Article Synopsis
- Appendiceal cancers, particularly mucinous cystadenocarcinoma, are rare and can cause serious complications like pseudomyxoma peritonei, leading to abdominal fluid accumulation called "jelly belly."
- A case of a young man with a persistent psoas abscess revealed mucinous adenocarcinoma with pseudomyxoma retroperitonei, emphasizing the need to consider malignancy in atypical abscesses.
- Early and accurate diagnosis is critical because these types of tumors can be misdiagnosed as common issues like abscesses, highlighting the importance of imaging and colonoscopy in identifying them.
Mucinous Cystadenoma Arising in Post-Treatment Non-Seminomatous Germ Cell Tumor: A Rare Occurrence.
Cureus
November 2024
Pathology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Germ cell tumors, the most common of the testicular neoplasms, originate from primordial germ cells. These tumors are known for their totipotent nature, capable of differentiating into various cell types. This case report presents a rare occurrence of mucinous cystadenoma in a patient who received chemotherapy for metastatic left non-seminomatous germ cell tumor (NSGCT) of the testis.
View Article and Find Full Text PDFALK-Rearranged Renal Cell Carcinoma: A Study of Three Cases With Clinicopathologic Features and Effect of Postoperative Adjuvant Immunotherapy.
Clin Genitourin Cancer
November 2024
Department of Pathology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Pathology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. Electronic address:
Article Synopsis
- ALK-rearranged renal cell carcinoma (ALK-RCC) is a rare kidney tumor recognized as a unique subtype in the WHO Classification of Tumors, characterized by its molecular features.* -
- A study of three ALK-RCC cases revealed diverse tumor characteristics, such as size, histological patterns, and immune profiles, with different ALK fusion partners identified through genetic sequencing.* -
- Follow-up outcomes varied: one patient survived without intervention, another responded positively to PD-1-targeted therapy, while the third experienced metastasis with little treatment benefit, highlighting the complexity of ALK-RCC.*
Mucinous adenocarcinoma in kidneys with developmental anomalies - a report of two cases.
BMC Urol
November 2024
Department of Urology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Article Synopsis
- Primary mucinous adenocarcinomas of the kidney are rare and their origins are unclear, with theories including chronic irritation and kidney maldevelopment.
- Two cases are presented: one involving a 50-year-old male with a duplex collecting system who had invasive mucinous carcinoma, and another case with a 53-year-old male who had a horseshoe kidney and recurrent mucinous adenocarcinoma after previous surgery.
- Both cases highlight the association between mucinous adenocarcinomas and kidney anomalies, emphasizing the importance of histopathology for diagnosis.
Literature review and robotic management of a rare case of primary retroperitoneal mucinous cystadenoma.
Radiol Case Rep
December 2024
Department of Surgery and Transplant, Willis Knighton Health System, Shreveport, LA, USA.
Primary retroperitoneal mucinous cystic tumors (PRMCT) are divided into 3 groups: benign, borderline malignancy, and malignant. We report a rare case of benign retroperitoneal mucinous cystadenoma of a 59-year-old Caucasian female who presented to our clinic with moderate intermittent left upper quadrant abdominal pain for several months, accompanied by early satiety, and unintentional weight loss of 10 pounds. An abdominal contrast-enhanced computed tomography (CT) scan indicated the presence of a 6.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!