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| http://dx.doi.org/10.1016/j.htct.2019.02.003 | DOI Listing |
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Multiplex Detection and Quantification of Virus Co-Infections Using Label-free Surface-Enhanced Raman Spectroscopy and Deep Learning Algorithms.
ACS Sens
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Department of Physics and Astronomy, Franklin College of Arts and Sciences, The University of Georgia, Athens, Georgia 30602, United States.
Multiple respiratory viruses can concurrently or sequentially infect the respiratory tract, making their identification crucial for diagnosis, treatment, and disease management. We present a label-free diagnostic platform integrating surface-enhanced Raman scattering (SERS) with deep learning for rapid, quantitative detection of respiratory virus coinfections. Using sensitive silica-coated silver nanorod array substrates, over 1.
View Article and Find Full Text PDFRisk Factors for Viral Coinfections in Blood Donors in Bahia, Brazil.
J Med Virol
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Programa de Pós-Graduação em Medicina e Saúde, Universidade Federal da Bahia, Salvador, Brazil.
Human Immunodeficiency Virus (HIV), Human T Lymphotropic Virus (HTLV), Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) coinfection may lead to disease progression or worsen its clinical presentation. Viral coinfections screening during blood donation is critical. To identify risk factors for coinfection among blood donors, we assessed the blood donations at the Fundação de Hematologia e Hemoterapia da Bahia, from 2008 to 2017.
View Article and Find Full Text PDFUpadacitinib: the JAK inhibitor that achieved what other drugs could not.
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Gastroenterology, Hospital Universitario Infanta Elena, Spain.
We present an interesting case of severe ulcerative colitis flare, of challenging management because of a cytomegalovirus co-infection, in which upadacitinib achieved clinical and biochemical remission after poor responses to ganciclovir and tofacitinib.
View Article and Find Full Text PDFScreening for broad-spectrum resistance to Turnip mosaic virus.
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September 2024
Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki Aza Aoba, Aobaku, Sendai, Miyagi 980-8572, Japan.
Turnip mosaic virus (TuMV) poses a major threat to crops like Chinese cabbage, causing significant economic losses. A viable and effective strategy to manage such diseases is by improvement of genetic-based viral resistance. To achieve this, it is important to have detailed and wide-ranging genetic resources, necessitating genetic exploration.
View Article and Find Full Text PDFSubclinical spp. Infections in a Community Setting in Bangui, Central African Republic.
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Parasitology Laboratory, Pasteur Institute of Bangui, Bangui, Central Africa Republic.
Background: Malaria is a major public health problem in the Central African Republic (CAR). Data on malaria epidemiology are often derived from confirmed cases of symptomatic malaria using passive detection approaches, with very limited knowledge of the extent of subclinical and submicroscopic infections.
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