Photoinduced Hydroxylation of Organic Halides under Mild Conditions.

Org Lett

College of Chemistry and Materials Engineering , Wenzhou University, Wenzhou 325035 , People's Republic of China.

Published: October 2019

AI Article Synopsis

  • The paper discusses a method for photoinduced hydroxylation of organic halides, which enables the creation of various functionalized phenols and alcohols.
  • The reactions can occur under mild conditions without needing a photocatalyst or strong bases.
  • A unique aspect of this process is the use of NaI, which facilitates this transformation effectively.

Article Abstract

Presented in this paper is photoinduced hydroxylation of organic halides, providing a mild access to a range of functionalized phenols and aliphatic alcohols. These reactions generally proceed under mild reaction conditions with no need for a photocatalyst or a strong base and show a wide substrate scope as well as excellent functional group tolerance. This work highlights the unique role of NaI that allows a challenging transformation to proceed under mild reaction conditions.

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http://dx.doi.org/10.1021/acs.orglett.9b03317DOI Listing

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