Lyme borreliosis is an infective disease that is usually transmitted to humans via biting by bacteria-infected tick. The disease is multisystemic and the affected organs are the skin (Erythema migrans), nervous system, eyes, heart and joints. is the bacterium that causes borreliosis and the hosts are rodents of the genus . In the Balkan region, is the most representative vector. A bite from an infected insect is the most common mode of transmitting ; however, transplacental transmission has also been documented. Pathogenesis of the disease consists of both direct and indirect mechanisms of immunological reactions which result in the production of IgM antibodies to in the first 3-6 weeks, and production of IgG class after 6 weeks. Many skin diseases and skin symptoms mimicking Lyme borreliosis, such as dermatomycosis, erysipelas, and undefined hyperpigmentation must be elaborated and considered for borreliosis, as skin symptoms of borreliosis can imitate many of them.
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http://dx.doi.org/10.4081/dr.2019.8021 | DOI Listing |
Infection
January 2025
Department of Infectious Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Purpose: To determine the frequency of confirmed Lyme neuroborreliosis (LNB) cases in adult patients with three different clinical presentations consistent with early LNB.
Methods: Data were obtained through routine health care at the UMC Ljubljana, Slovenia from 2005 to 2022, using clinical pathways. The patients were classified into three groups: (i) radicular pain of new onset (N = 332); or (ii) involvement of cranial nerve(s) but without radicular pain (N = 997); or (iii) erythema migrans (EM) skin lesion(s) in conjunction with symptoms suggestive of nervous system involvement but without either cranial nerve palsy or radicular pain (N = 240).
Acta Trop
December 2024
Centro de Investigación en Alimentación y Desarrollo, A. C. (CIAD), 83304 Hermosillo, Sonora, Mexico. Electronic address:
Ticks are significant ectoparasites that transmit a variety of pathogens, leading to serious human and animal diseases, including Lyme disease, Rocky Mountain spotted fever, anaplasmosis and many others. The emergence of acaricide resistance in hard ticks presents a formidable challenge for public health and livestock management, exacerbated by the increasing incidence of tick-borne diseases and associated economic losses, estimated at $20 billion annually in the livestock sector alone. This review examines the mechanisms underlying acaricide resistance, focusing on genetic mutations, metabolic detoxification processes, and behavioral adaptations in tick populations.
View Article and Find Full Text PDFJ Med Entomol
January 2025
Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA.
A previous laboratory study using Haemaphysalis longicornis Neumann (Acari: Ixodidae) ticks of North American origin showed that larvae could acquire the Lyme disease spirochete, Borrelia burgdorferi sensu stricto (s.s.) (Spirochaetales: Spirochaetaceae) while feeding to completion on infected mice.
View Article and Find Full Text PDFCureus
December 2024
Emergency Medicine, Whiston Hospital; Mersey and West Lancashire Teaching Hospitals NHS Trust, Whiston, GBR.
Kikuchi-Fujimoto disease (KFD) is a rare, self-limiting, and ultimately benign condition characterised by localised lymphadenopathy. The association of KFD with aseptic meningitis is even more uncommon. We report a case of KFD accompanied by aseptic meningitis in a 31-year-old male who initially presented with lethargy, night sweats, axillary lymphadenopathy, and oral ulcers.
View Article and Find Full Text PDFNeoreviews
January 2025
Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Borrelia miyamotoi disease (BMD), also known as hard-tick relapsing fever, is an emerging tick-borne illness caused by the bacterium Borrelia miyamotoi. This pathogen is transmitted primarily by Ixodes ticks, also known as deer ticks or black-legged ticks. BMD poses significant public health concerns because of its potential to cause severe hemodynamic and hematologic disturbances, particularly in vulnerable populations such as pregnant individuals.
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