The stability of a shear flow imposed along a diffusive interface that separates two miscible liquids (a heavier liquid lies underneath) is studied using direct numerical simulations. The phase-field approach is employed for description of a thermo- and hydrodynamic evolution of a heterogeneous binary mixture. The approach takes into account the dynamic interfacial stresses at a miscible interface and uses the extended Fick's law for setting the diffusion transport (the diffusion flux is proportional to the gradient of chemical potential). The shear flow is unstable to two kinds of instabilities: (1) the Kelvin-Helmholtz instability, with an immovable vortex formed in the middle of an interface (in the vertical direction) and (2) the Holmboe instability, with traveling waves along the interfacial boundary. The development of the Holmboe instability results in a stronger enhancement of molecular mixing between the mixture components. Earlier, the boundaries of these instabilities were determined using the linear stability analysis and employing the concept of a "frozen interface." In the current work, through the solution of full equations, we obtain the stability boundaries for several sets of governing parameters, showing a greater variety of the possible shapes of the stability diagrams. The Kelvin-Helmholtz instability always occurs at lower gravity effects (lower density contrasts), while the Holmboe instability occurs when gravity is stronger. We show that for some parameters these two instabilities are separated by a zone where the shear flow is stable, and this zone disappears for the other sets of parameters.
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http://dx.doi.org/10.1103/PhysRevE.100.023103 | DOI Listing |
Soft Matter
January 2025
Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Microfluidic chips are powerful tools for investigating numerous variables including chemical and physical parameters on protein aggregation. This study investigated the aggregation of bovine serum albumin (BSA) in two different systems: a vial-based static system and a microfluidic chip-based dynamic system in which BSA aggregation was induced successfully. BSA aggregation induced in a microfluidic chip on a timescale of seconds enabled a dynamic investigation of the forces driving the aggregation process.
View Article and Find Full Text PDFHeliyon
January 2025
Institute of Mathematics, Henan Academy of Sciences, Zhengzhou, 450046, China.
This study examines the behavior of the Casson nanofluid bioconvection flow around a spinning disc under various influences, including gyrotactic microorganisms, multiple slips, and thermal radiation. Notably, it accounts for the reversible nature of the flow and incorporates the esterification process. The aim of this study is to investigate the influence of reversible chemical reactions on the flow behavior of a Casson nanofluid in the presence of bioconvective microorganisms over a spinning disc.
View Article and Find Full Text PDFSci Rep
January 2025
State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu, 610500, China.
Hydraulic fracturing, which forms complex fracture networks, is a common technique for efficiently exploiting low-permeability conglomerate reservoirs. However, the presence of gravel makes conglomerate highly heterogeneous, endowing the deformation, failure, and internal micro-scale fracture expansion mechanisms with uniqueness. The mechanism of fracture expansion when encountering gravel in conglomerate reservoirs remains unclear, challenging the design and effective implementation of hydraulic fracturing.
View Article and Find Full Text PDFSci Rep
January 2025
Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, Strasbourg, F-67065, France.
Different approaches are being developed to efficiently produce in vitro platelets from cultured megakaryocytes to meet the constant demand of platelet transfusion and serve for research purposes. Recent works have shown that turbulence and periodic stress can significantly enhance platelet yield. Here we have developed and characterized a platelet production device that takes in account these properties.
View Article and Find Full Text PDFComput Methods Programs Biomed
January 2025
College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China; Beijing International Science and Technology Cooperation Base for Intelligent Physiological Measurement and Clinical Transformation, Beijing 100124, China. Electronic address:
Background And Objective: In clinical practice, valve-sparing aortic root replacement surgery primarily addresses left ventricular dysfunction in patients due to severe aortic regurgitation, but there is controversy regarding the choice of surgical technique. In order to investigate which type of valve-sparing aortic root replacement surgeries can achieve better blood flow conditions, this study examines the impact of changes in the geometric morphology of the aortic root on the hemodynamic environment through numerical simulation.
Methods: An idealized model of the aortic root was established based on data obtained from clinical measurements, including using the model of the aortic root without significant lesions as the control group (Model C), while using surgical models of leaflet reimplantation with tubular graft (Model T), leaflet reimplantation with Valsalva graft (Model V), and the Florida sleeve procedure (Model F) as the experimental groups.
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