Coxiella burnetii is an intracellular bacterium that causes acute and chronic Q fever. This unique pathogen has been historically challenging to study due to obstacles in genetically manipulating the organism and the inability of small animal models to fully mimic human Q fever. Here, we review the current state of C. burnetii research, highlighting new approaches that allow the mechanistic study of infection in disease relevant settings.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101257 | PMC |
| http://dx.doi.org/10.1016/j.micinf.2019.09.001 | DOI Listing |
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