Background And Aims: Pectoral nerve (PecS II) block is the latest modality for providing postoperative analgesia after breast surgery. The present study was planned to compare the analgesic efficacy of thoracic paravertebral block (TPVB) and PecS II for postoperative analgesia after modified radical mastectomy (MRM).
Methods: A total of 40 female patients undergoing radical mastectomy were randomly allocated into two groups ( = 20). Group T received ultrasound-guided TPVB, while group P received PecS II block using 0.25% levobupivacaine 24 ml + dexamethasone 1 ml (4 mg) before induction of anesthesia. The primary outcome was duration of analgesia (time to request first analgesic dose), while total rescue analgesic consumption in first 24 h, numeric rating score (NRS), and complication were secondary outcomes. The data were analyzed using IBM SPSS software version 22.0.
Results: The duration of analgesia was significantly prolonged in the group P than group T (474.1 ± 84.93 versus 371.5 ± 51.53 min, respectively; < 0.0001). Postoperative morphine consumed at 24 h was less in the group P than group T (11.25 ± 4.75 and 15.0 ± 4.86 mg, respectively; = 0.018). NRS at movement and rest were lower in the group P as compared to group T at all time intervals (median 3 versus 4). No block-related complication was recorded in any group.
Conclusions: The 0.25% levobupivacaine with dexamethasone 4 mg in PecS II block provided longer duration of analgesia than the TPVB in patients undergoing MRM without any adverse effects.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753749 | PMC |
| http://dx.doi.org/10.4103/sja.SJA_25_19 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparative Effectiveness of Analgesia for Early Pain Management After Pediatric Tonsillectomy: A Systematic Review and Network Meta-Analysis.
Anesth Analg
December 2024
From the Department of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China.
Article Synopsis
- Effective pain management post-tonsillectomy in children is crucial, and this study aimed to determine the best analgesics for such procedures.
- The research involved a systematic review and meta-analysis of 82 studies, examining various analgesic methods and their impact on pain relief and complications in over 6,100 pediatric patients.
- Key findings showed that local anesthetics, opioids (like morphine), and glucocorticoids (such as dexamethasone) were effective in reducing pain, while dexamethasone also decreased postoperative complications compared to other methods.
Ultrasound-Guided Regional Anesthesia Using a Mixture of Dexamethasone, Dexmedetomidine, and 0.2% Levobupivacaine for Bilateral Breast Cancer Surgery Under a Spontaneous Breathing Opioid-Free Anesthesia: A Case Report.
Cureus
April 2024
Department of Critical Care, AORN Ospedali dei Colli, Naples, ITA.
Breast cancer is unfortunately the most common cancer in women, although survival rates have greatly increased in recent years. Breast surgery can be very aggressive and therefore highly painful, leading to high rates of acute postsurgical pain and chronic pain. In addition to general anesthesia (GA), ultrasound-guided regional anesthesia (RA) is sometimes performed to help reduce acute postoperative pain and consumption of opioids.
View Article and Find Full Text PDFDexmedetomidine vs Dexamethasone as an Adjuvant to Levobupivacaine in Ultrasound-Guided Transversus Abdominis Plane Block for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomies.
Anesth Pain Med
December 2023
Department of Gynecology, Himalayan Institute of Medical Sciences, Jollygrant, Dehradun.
Article Synopsis
- This study evaluates pain management after total abdominal hysterectomy using dexamethasone and dexmedetomidine alongside levobupivacaine in transversus abdominis plane blocks.
- Patients were divided into two groups, receiving either dexamethasone or dexmedetomidine, and their pain levels, along with tramadol usage and satisfaction, were assessed.
- Results showed that the dexmedetomidine group experienced lower pain scores and lesser need for additional pain medication, indicating it may be a more effective option for postoperative pain relief.
A Comparison Between Dexamethasone and Clonidine as Adjuvants to Levobupivacaine in the Supraclavicular Approach to the Brachial Plexus Block: A Double-Blind Study.
Cureus
October 2023
Anesthesiology, King George's Medical University (KGMU), Lucknow, IND.
Objective: The objective of this clinical study is to compare the efficacy of adding dexamethasone or clonidine as an adjuvant drug to levobupivacaine in supraclavicular brachial plexus block (BPB) with regard to the onset and duration of sensory and motor blocks along with duration of postoperative analgesia.
Background: Brachial plexus block (BPB), with or without general anesthesia, has been used widely for multiple upper limb surgical procedures, by virtue of its efficacy in terms of cost-effectiveness, efficiency, safety margins, and good postoperative analgesia. Various adjuvant drugs have been described to potentiate the analgesic effect of local anesthetic agents such as epinephrine, clonidine, dexamethasone, dexmedetomidine, or midazolam.
Background: Interscalene brachial plexus block (ISB) for arthroscopic rotator cuff repair (ARCR) provides high analgesic efficacy for postoperative pain. However, different drug efficacies remain unclear. This retrospective study compared the efficacy of ropivacaine and levobupivacaine in a single-dose ISB for pain control after ARCR.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!