AI Article Synopsis

  • Clonality levels of 25% or higher in patients are linked to a lower chance of achieving a very good partial response to ibrutinib treatment.
  • *Patients with high clonality also experience shorter progression-free survival while on ibrutinib.
  • *Assessing clonality can serve as a new biomarker to help predict treatment outcomes for patients with Waldenström macroglobulinemia using ibrutinib.

Article Abstract

clonality ≥25% is associated with lower very good partial response and shorter progression-free survival to ibrutinib. clonality assessment represents a novel biomarker to predict outcomes to ibrutinib in Waldenström macroglobulinemia patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784519PMC
http://dx.doi.org/10.1182/bloodadvances.2019000635DOI Listing

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