AI Article Synopsis
- The study assesses the antifungal properties of a brown alga extract obtained through supercritical fluid extraction at specific conditions (50 °C, 300 bar).
- The extract was tested at various concentrations (0.05%, 0.2%, 0.5%, 1.0%) against pathogenic fungi, revealing that 0.5% and 1.0% concentrations completely inhibited growth within 144 hours and caused degradation of the fungi.
- Additionally, fucosterol, a compound from the alga, showed antifungal effects, particularly at 1.0%, and even lower concentrations led to shorter, degraded macroconidia.
Article Abstract
In this study, potential antifungal properties of a brown alga were evaluated. The algal extract was obtained with the use of supercritical fluid extraction (scCO) at a temperature of 50 °C under a pressure of 300 bar. The aqueous solution of the extract at the concentration of 0.05%, 0.2%, 0.5% and 1.0% was studied against pathogenic fungi on a liquid RB medium. This study is the first report on antifungal properties of the brown algae scCO extract against and phytopathogens. The concentrations of the studied extract (0.5% and 1.0%) were demonstrated to have an ability to inhibit 100% growth of macroconidia within 144 h, as well as an ability to cause their total degradation. As a result of the study, the antifungal effect of fucosterol against was also indicated. The total macroconidia growth was inhibited by 1.0% fucosterol. Moreover, at lower concentrations (0.05-0.2%) of fucosterol, macroconidia were characterized by shorter length and structural degradation was observed. The mycelial growth of (Fo38) by 1% scCO extract was analyzed at the level of 48% after 168 h of incubation, whereas 100% extract was found to be effective in (CBS122) and (Fo38) growth inhibition by 72% and 75%, respectively after 168 h of incubation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804000 | PMC |
| http://dx.doi.org/10.3390/molecules24193518 | DOI Listing |
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