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Technology and Dementia Preconference.
Alzheimers Dement
December 2024
Deutsches Zentrum für Neurodegenerative Erkrankungen e. V. (DZNE), site Rostock / Greifswald, Rostock, Germany.
Background: Familial Alzheimer's disease research necessitates innovative methodologies to disentangle the intricate relationships between genetic factors and neuroimaging measures. Traditional frequentist approaches, often hampered by small sample sizes in this population and challenges in incorporating prior knowledge transparently, may limit the robustness of findings.
Methods: We analyzed neuroimaging data of preclinical PSNE1 single mutation carriers, utilizing the software JASP to test effects of carrier status on measures of basal forebrain functional connectivity using both frequentist and Bayesian approach.
Diacylglycerol kinase δ is required for skeletal muscle development and regeneration.
FASEB Bioadv
January 2025
Department of Chemistry, Graduate School of Science Chiba University Chiba Japan.
Diacylglycerol kinase δ (DGKδ) phosphorylates diacylglycerol to produce phosphatidic acid. Previously, we demonstrated that down-regulation of DGKδ suppresses the myogenic differentiation of C2C12 myoblasts. However, the myogenic roles of DGKδ in vivo remain unclear.
View Article and Find Full Text PDFDental implant in esthetic zone: A case report.
SAGE Open Med Case Rep
January 2025
PhD in Health Science Program, Faculty of Medicine, Mahasarakham University, Mahasarakham, Thailand.
This case report emphasizes the complexities involved in dental implant placement within the anterior esthetic zone, focusing on the integration of advanced surgical techniques and meticulous prosthetic design for optimal esthetic and functional results. A 28-year-old male presented with the absence of the upper left central incisor, which had been extracted 5 years prior due to fracture. Clinical and radiographic assessments indicated normal alveolar bone levels; however, the esthetic demands required a specialized approach.
View Article and Find Full Text PDFCone-Beam Computed Tomography Evaluation of the Mandibular Condyle and Articular Spaces Following Orthognathic Surgery Using Freehand Articulation Method in Patients With Class II and III Skeletal Deformity.
Int J Dent
December 2024
Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
This study aimed to assess the changes in the position and size of articular spaces and anteroposterior and mediolateral condyle dimensions following orthognathic surgery. Additionally, it evaluated the correlation between these changes and mandibular movement during surgery. This experimental study examined 31 patients (16 with Class III and 15 with Class II malocclusions) who were candidates for orthognathic surgery.
View Article and Find Full Text PDFDynamic biomechanical effects of medial meniscus tears on the knee joint: a finite element analysis.
J Orthop Surg Res
January 2025
Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China.
Background: Meniscus tears can change the biomechanical environment of the knee joint and might accelerate the development of osteoarthritis. The aim of this study was to investigate the dynamic biomechanical effects of different medial meniscus tear positions and tear gaps on the knee during walking.
Methods: Seven finite element models of the knee joint were constructed, including the intact medial meniscus (IMM), radial stable tears in the anterior, middle, and posterior one-third regions of the medial meniscus (RSTA, RSTM, RSTP), and the corresponding unstable tears (RUTA, RUTM, RUTP).
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