Approach to optimize 3-dimensional brain functional activation image with high resolution: a study on functional near-infrared spectroscopy.

Biomed Opt Express

Department of Cogno-Mechatronics Engineering, Pusan National University, San 30 Jangjeon-dong Geumjeong-gu, Busan 609-735, South Korea.

Published: September 2019

In this study, 3-dimensional (3-D) enhanced brain-function-map generation and estimation methodology is presented. Optical signals were modelled in the form of numerical optimization problem to infer the best existing waveform of canonical hemodynamic response function. Inter-channel activity patterns were also estimated. The estimation of activation of inter-channel gap depends on the minimization of generalized cross-validation. 3-D brain activation maps were produced through inverse discrete cosine transform. The proposed algorithm acquired significant results for 3-D functional maps with high resolution, in comparison with that of 2-D functional -maps. A comprehensive analysis by exhibiting images corresponding to several layers has also been appended.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757466PMC
http://dx.doi.org/10.1364/BOE.10.004684DOI Listing

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