Situs inversus is a rare condition. It is characterised by reverse handed positioning of the internal viscera. Laparoscopic cholecystectomy is the standard procedure for cholelithiasis, but it may lead to technical difficulties in case of situs inversus, especially to right-handed surgeons. A 40-year female presented to the department with epigastric pain and bloating usually after fatty meals. Diagnosis of symptomatic gall bladder stone was made. She was a known case of situs inversus. Laparoscopic cholecystectomy was performed by right-handed surgeon with uneventful recovery.
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