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First clinical utility of sensing Ultrasound Localization Microscopy (sULM): identifying renal pseudotumors.
Theranostics
January 2025
Sorbonne Université, CNRS, INSERM, Laboratoire d'Imagerie Biomédicale, Paris, France.
Renal pseudotumors, which mimic tumors on imaging, pose diagnostic challenges that can lead to unnecessary interventions. Sensing ultrasound localization microscopy (sULM) is an advanced imaging technique that uses ultrasound imaging and microbubbles as sensors to visualize kidney functional units. This study aims to investigate whether sULM could differentiate between renal pseudotumors and tumors based on the presence of glomeruli.
View Article and Find Full Text PDFRenal sarcoidosis: renal pathology guides diagnosis and prognosis.
Diagn Pathol
December 2024
Department of Nephrology, Peking University People's Hospital, Beijing, China.
Background: While many studies have reported renal involvement in sarcoidosis, there is limited description of the pathological manifestations of renal sarcoidosis (RS). This study aimed to explore the standardized pathological diagnosis of RS while evaluating the relationship among pathology, clinical manifestations, and prognosis.
Methods: We conducted a retrospective, single-center study of RS in renal biopsy cases treated in our department between January 2019 and December 2023.
The pathogenesis of gout.
J Rheum Dis
January 2025
Division of Rheumatology, Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
Gout is the most common inflammatory arthritis in adults, associated with hyperuricemia and the chronic deposition of monosodium urate (MSU) crystals. Hyperuricemia results from increased production of uric acid and decreased excretion by the kidneys and intestines. Urate excretion is regulated by a group of urate transporters, and decreased renal or intestinal excretion is the primary mechanism of hyperuricemia in most people.
View Article and Find Full Text PDFInvestigation of the Relationship Between Brown HT Dye Exposure and Mammary Tumor Development in Female Rats: An Assessment of the Potential Risk of Breast Cancer.
Cureus
November 2024
Department of Applied Nutrition and Food Technology, Islamic University, Kushtia, BGD.
Article Synopsis
- * Female Long-Evans rats were divided into groups to assess the effects of E155 on tumor development, with some receiving the dye in various doses over 40 weeks compared to control groups.
- * Results showed that higher E155 doses led to significant weight loss, renal impairment, liver dysfunction, and an increased incidence of mammary tumors, suggesting that prolonged exposure could heighten breast cancer risk.
A Case of Acute Eosinophilic Granulomatous Tubulointerstitial Nephritis in a Patient Receiving Combination Treatment with Three Drugs.
Intern Med
December 2024
Nephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
We herein report a 69-year-old man with acute kidney injury who required dialysis after receiving a combination of three drug-induced lymphocyte stimulation test-positive drugs. A kidney biopsy showed tubulointerstitial nephritis with severe eosinophilic infiltration and numerous granuloma formations. Acute eosinophilic granulomatous tubulointerstitial nephritis was diagnosed.
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