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Risk Factors and Outcomes of Acute Pulmonary Embolism in African Patients: A Systematic Review.
Cureus
November 2024
Cardiothoracic Surgery Unit, Department of Surgery, University of Port Harcourt Teaching Hospital, Port Harcourt, NGA.
Pulmonary embolism is a common cause of morbidity and mortality. Numerous risk factors have been identified that predispose patients to this disease. This study aims to identify these risk factors and the possible outcomes (recovery or mortality) after receiving treatment from any hospital.
View Article and Find Full Text PDFRevealing the Therapeutic Potential of Stem Cells in Burn Healing: A Deeper Understanding of the Therapeutic Mechanisms of Epidermal Stem Cells and Mesenchymal Stem Cells.
Stem Cells Int
December 2024
Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai 200433, China.
Burns are a global public health issue and a major cause of disability and death around the world. Stem cells, which are the undifferentiated cells with the potential for indefinite proliferation and multilineage differentiation, have the ability to replace injured skin and facilitate the wound repair process through paracrine mechanisms. In light of this, the present study aims to conduct a bibliometric analysis in order to identify research hotspots of stem cell-related burns and assess global research tendencies.
View Article and Find Full Text PDFCrosstalk between gut microbiota and cancer chemotherapy: current status and trends.
Discov Oncol
December 2024
Department of Traditional Chinese Medicine, Peking University First Hospital, Beijing, China.
Background: Chemotherapy is crucial in the management of tumors, but challenges such as chemoresistance and adverse reactions frequently lead to therapeutic delays or even premature cessation. A growing body of research underscores a profound connection between the gut microbiota (GM) and cancer chemotherapy (CC). This paper aims to pinpoint highly influential publications and monitor the current landscape and evolving trends within the realm of GM/CC research.
View Article and Find Full Text PDFProtocol for a systematic review and meta-analysis of the combination of ezetimibe and statins for hyperlipidemia.
PLoS One
December 2024
Fuzhou Medical College, Nanchang University, Fuzhou, Jiangxi, China.
Introduction: Hyperlipidemia is increasingly recognized as a significant global health issue, often associated with conditions such as hypertension, diabetes, and obesity. While statins are frequently prescribed to manage lipid levels, recent studies indicate that reliance solely on statin therapy may present certain disadvantages, including prolonged treatment durations, the potential for drug resistance, and various adverse effects. Research indicates that the combination of ezetimibe and statins demonstrates a favorable therapeutic effect in the management of hyperlipidemia.
View Article and Find Full Text PDFTackling algorithmic bias and promoting transparency in health datasets: the STANDING Together consensus recommendations.
Lancet Digit Health
January 2025
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK; National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre, Birmingham, UK; Centre for Patient Reported Outcomes Research, School of Health Sciences, College of Medical and Dental Sciences, Birmingham, UK; University of Birmingham, Birmingham, UK. Electronic address:
Without careful dissection of the ways in which biases can be encoded into artificial intelligence (AI) health technologies, there is a risk of perpetuating existing health inequalities at scale. One major source of bias is the data that underpins such technologies. The STANDING Together recommendations aim to encourage transparency regarding limitations of health datasets and proactive evaluation of their effect across population groups.
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