Enhanced Actin Dynamics: A Therapeutic Strategy for Axonal Regeneration?

Neuron

Department of Neurogenetics, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany. Electronic address:

Published: September 2019

AI Article Synopsis

  • Spinal cord injuries result in lasting paralysis because neurons in the central nervous system can't repair damaged axons.
  • A recent study by Tedeschi et al. (2019) suggests that using actin-depolymerizing proteins can promote axon regrowth in mice.
  • This research indicates a potential therapeutic approach to help regenerate nerve connections after spinal cord injuries.

Article Abstract

Spinal cord injury causes permanent paralysis due to the inability of neurons in the central nervous system to regenerate transected axons. In this issue of Neuron, Tedeschi et al. (2019) report that axonal regrowth can be stimulated by actin-depolymerizing proteins, at least in mice.

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Source
http://dx.doi.org/10.1016/j.neuron.2019.09.008DOI Listing

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