Recently there has been an increasing amount of research on copeptin as a novel biomarker for stress response and homeostasis disorders in a wide spectrum of morbidities. Copeptin is a stable and easily measured surrogate marker of arginine vasopressin and is increasingly included as a part of routine patient assessment tests in selected clinical scenarios. Such tests are also performed in the perioperative period, in which complication risk assessment is of exceptional importance. This review is an attempt to appraise up to date publications on use of copeptin as a biomarker.

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