Background: Drug-resistant tuberculosis (DR-TB) imposes formidable burden on national health systems.
Objectives: This study aims to evaluate clinical profile and treatment outcome of drug resistant tuberculosis patients at tertiary care centre using a standardised treatment regimen (STR).
Methods: Retrospective analysis of 146 patients with DR-TB from Solapur district who were treated with STR from period of September 2012 to December 2014 was done. Statistical analysis of treatment outcome data was done to know predictors of treatment success of DR-TB.
Results: Out of total 146 bacteriologically proven cases of DR-TB, 95 were males and 51 females. 41% of patients were residents of Solapur city and the rest from different parts of Solapur district. Out of the 146 patients, 130 (89%) patients achieved sputum culture conversion within three months. Treatment outcome of these patients was as followstreatment success in 84 (58%), 20(14%) died, 28(19%) defaulted and failure in 14(9%) patients. Three predictors were identified for successful treatment outcome of DR-TB that include urban residence, patients with chest x-ray findings of moderately advanced disease and patients whose DR-TB status diagnosed by genexpert technology.
Conclusion: In resource-poor settings, well-designed STR under national programme provides satisfactory results.
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