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Digital Home-Based Self-Monitoring System for People with Heart Failure: Protocol for Development of SmartHeart and Evaluation of Feasibility and Acceptability.
JMIR Res Protoc
January 2025
School of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition, Deakin University, Burwood, Australia.
Background: Heart failure (HF) is a chronic, progressive condition where the heart cannot pump enough blood to meet the body's needs. In addition to the daily challenges that HF poses, acute exacerbations can lead to costly hospitalizations and increased mortality. High health care costs and the burden of HF have led to the emerging application of new technologies to support people living with HF to stay well while living in the community.
View Article and Find Full Text PDFReceived and Desired Support Needs of Postoperative Bariatric Surgery Patients.
Gastroenterol Nurs
January 2025
About the authors: Katherine K. Sink, PhD, APRN-CNS, is a Retired Professor, University of Toledo, Toledo, Ohio.
Obesity is a worldwide health concern with one highly effective solution being bariatric surgery. The purpose of this descriptive study was to explore the experiences of postoperative bariatric surgery patients related to perceptions of helpful interventions for achieving and maintaining weight loss. Fifteen participants shared their perceived support received and their perceptions of desired support needed after bariatric surgery.
View Article and Find Full Text PDFPrP Glycoprotein Is Indispensable for Maintenance of Skeletal Muscle Homeostasis During Aging.
J Cachexia Sarcopenia Muscle
February 2025
Department of Bioactive Material Sciences, Research Center of Bioactive Materials, Jeonbuk National University, Jeonju, Republic of Korea.
Background: The cellular prion protein (PrP), a glycoprotein encoded by the PRNP gene, is known to modulate muscle mass and exercise capacity. However, the role of PrP in the maintenance and regeneration of skeletal muscle during ageing remains unclear.
Methods: This study investigated the change in PrP expression during muscle formation using C2C12 cells and evaluated muscle function in Prnp wild-type (WT) and knock-out (KO) mice at different ages (1, 9 and 15 months).
Association between sedentary behavior, physical activity, and osteoarthritis: results from NHANES 2007-2020 and Mendelian randomization analysis.
Front Public Health
January 2025
Department of Nursing, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, China.
Introduction: Osteoarthritis (OA) is a prevalent and debilitating disorder that affects the joints and has a complex array of causes. While sedentary behavior (SB) and physical activity (PA) have been implicated in OA risk, the relationship between these factors and OA development remains unclear. This study investigates the correlation and potential causality between SB, PA, and OA using both cross-sectional and Mendelian randomization (MR) analysis.
View Article and Find Full Text PDFMulti-omics analysis reveals the anti-fatigue mechanism of BCAA-enriched egg white peptides: the role of the gut-muscle axis.
Food Funct
January 2025
Jilin Provincial Key Laboratory of Nutrition and Functional Food, Jilin University, Changchun, 130062, People's Republic of China.
Bioactive peptides rich in branched-chain amino acids (BCAAs) are an effective way to alleviate fatigue conditions, but the deep mechanism remains unclear. This study investigated the anti-fatigue effect of branched-chain amino acid-enriched egg white peptides (BEWPs) through the gut-muscle axis by gut bacteria and untargeted metabolomic analyses. The results demonstrated that BEWPs enhanced exercise endurance and strength by also promoting gastrocnemius development in mice.
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