Sarcoidosis is an inflammatory multisystemic disease of unknown etiology with multiple presentations of cutaneous lesions. It characteristically infiltrates scars due to several kind of trauma such as surgery, tattoo and even herpes zoster. We present a case of a 65-year-old woman with progressive distal paresthesia and motor weakness. She was referred to our dermatology clinic for a new violaceous nodular plaque within an old melanoma scar on the posterior neck. On positron emission tomography-computed tomography, there were multiple enlarged thoracic lymphadenopathy and a fluorodeoxyglucose-avid cutaneous lesion on the posterior neck, right in the melanoma scar. Cutaneous and nerve biopsies showed non-necrotising granulomas, supporting the diagnosis of systemic sarcoidosis and excluding melanoma recurrence with metastasis. It is the first case of cutaneous sarcoidosis arising within a melanoma scar. Interestingly, patients with melanoma have a higher risk of sarcoidosis.
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http://dx.doi.org/10.1177/2050313X19877274 | DOI Listing |
J Dtsch Dermatol Ges
January 2025
Department of Dermatology, National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.
Eur Burn J
October 2024
St. Andrew's Centre for Plastic Surgery and Burns, Mid and South Essex NHS Foundation Trust, Chelmsford CM1 7E, UK.
(1) Background: Effective wound management aims for expedited healing, improved functional and scar outcomes, and reduced complications including infection. Delayed wound healing remains a prevalent problem in the elderly. Suprathel is a synthetic absorbable skin substitute and an attractive option in partial thickness wounds.
View Article and Find Full Text PDFMycosis fungoides (MF), a form of cutaneous T-cell lymphoma (CTCL), increases the risk of other malignancies. A common and effective treatment for patients with MF is radiotherapy (RT), which itself also increases the risk of malignancies. One such malignancy that may result from both MF and RT is cutaneous squamous cell carcinoma (cSCC).
View Article and Find Full Text PDFEur J Surg Oncol
January 2025
Department of Surgery, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden; Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Introduction: Determining sentinel lymph node (SLN) status is important for treatment decisions in patients with melanoma. Superparamagnetic iron oxide nanoparticles (SPIO) combined with MRI have emerged as an alternative to Technetium lymphoscintigraphy for preoperative mapping of SLN, however, the MRI protocols so far are extensive with long in-camera time. This study aimed to evaluate an optimized MRI protocol for rapid identification of SLNs using SPIO as a tracer, without compromising diagnostic quality, the GOthenburg Fast Acquisition Sentinel lymph node Tracking MRI (GO-FAST-MRI).
View Article and Find Full Text PDFCureus
October 2024
Surgery, Hospital General Dr. Fernando Quiroz Gutiérrez, Mexico City, MEX.
Cutaneous squamous cell carcinoma (cSCC) is the second most common cutaneous non-melanoma cancer in Mexico, accounting for 20% of all skin cancers. It is considered a global public health concern due to the rising incidence and prevalence, which is associated with an aging population. Treatment for cSCC depends on the severity of the disease, which determines different therapeutic approaches.
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