We identified two new (CT) variants escaping Aptima Combo 2 (AC2) assay detection, in clinical specimens of two patients. One had a C1514T mutation the other a G1523A mutation, both within the AC2 23S rRNA target region. The prevalence of such variants among persons tested for CT in England was estimated to be fewer than 0.003%.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761577 | PMC |
| http://dx.doi.org/10.2807/1560-7917.ES.2019.24.38.1900557 | DOI Listing |
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