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Sarcopenia, which diminishes lifespan and healthspan in the elderly, is commonly exacerbated by viral pneumonia, including influenza and COVID-19. In a study of influenza A pneumonia in mice, young mice fully recovered from sarcopenia, while older mice did not. We identified a population of tissue-resident skeletal muscle macrophages that form a spatial niche with satellite cells and myofibers in young mice but are lost with age.
View Article and Find Full Text PDFRestoration of Genuine Sensation and Proprioception of Individual Fingers Following Transradial Amputation with Targeted Sensory Reinnervation as a Mechanoneural Interface.
J Clin Med
January 2025
Department of Trauma Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
: Tactile gnosis derives from the interplay between the hand's tactile input and the memory systems of the brain. It is the prerequisite for complex hand functions. Impaired sensation leads to profound disability.
View Article and Find Full Text PDFEffect of reserve protection level and governance on tree cover loss and gain.
Conserv Biol
January 2025
School of Geography, Planning, and Spatial Sciences, University of Tasmania, Hobart, Tasmania, Australia.
Terrestrial protected areas are essential for biodiversity conservation, yet it is not fully understood when and how different types of protected areas are most effective in achieving specific conservation objectives. We assessed the impact of reserves on tree cover loss and gain through a case study in Tasmania, Australia. We considered varying protection levels (strict, where human activities are restricted, and multiple use) and governance types (public and private).
View Article and Find Full Text PDFRisk Assessment of Harmful Algal Blooms in Salmon Farming: Scotland as a Case Study.
Toxins (Basel)
January 2025
Scottish Association for Marine Science-UHI, Oban PA37 1QA, UK.
This study explored harmful algal bloom (HAB) risk as a function of exposure, hazard and vulnerability, using Scotland as a case study. Exposure was defined as the fish biomass estimated to be lost from a bloom event, based on the total recorded annual production. Hazard was estimated from literature-reported bloom events.
View Article and Find Full Text PDFMapping Drug-Resistant Tuberculosis Treatment Outcomes in Hunan Province, China.
Trop Med Infect Dis
December 2024
School of Population Health, Faculty of Health Sciences, Curtin University, Perth, WA 6102, Australia.
Background: Drug-resistant tuberculosis (DR-TB) remains a major public health challenge in China, with varying treatment outcomes across different regions. Understanding the spatial distribution of DR-TB treatment outcomes is crucial for targeted interventions to improve treatment success in high-burden areas such as Hunan Province. This study aimed to map the spatial distribution of DR-TB treatment outcomes at a local level and identify sociodemographic and environmental factors associated with poor treatment outcomes in Hunan Province, China.
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