C3 polymorphism in Kotas and Badagas of Nilgiri Hills, south India.

Blood serum samples from Kota (n = 95) and Badaga (n = 113) groups of the Nilgiri Hills, South India, were screened for C3 polymorphism using polyacrylamide slab gel electrophoresis. The distribution of the three common phenotypes F, FS and S and a variant phenotype is reported. Two deficient individuals, one per subsample, have been found. The allelic frequencies for C3*F and C3*S in Kotas and Badagas are 0.1075, 0.8925 and 0.0982, 0.9018 respectively. The results are discussed in the light of available literature on C3 polymorphism in other Indian populations.