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Pylephlebitis treated with apixaban. | LitMetric

Pylephlebitis treated with apixaban.

Hosp Pract (1995)

Jefferson Vascular Center, Thomas Jefferson University Hospitals, Philadelphia, PA, USA.

Published: October 2019

Pylephlebitis is a rare condition that is characterized by an infected thrombus of the portal vein system and was traditionally associated with a high mortality rate prior to the introduction of antibiotics. This report details a 77-year-old Chinese male found to have a splenic vein thrombosis, bacteremia, and a polymicrobial splenic abscess. The patient was treated with abscess drainage and a 6 week course of intravenous antibiotics, and a direct oral anticoagulant, apixaban 2.5 mg twice daily. To our knowledge, this is the second documented case of pylephlebitis treated with apixaban. Here, we summarize our experience treating this case of pylephlebitis and briefly report on the existing body of literature.

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Source
http://dx.doi.org/10.1080/21548331.2019.1670476DOI Listing

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