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Angiotensin-(1-7) for diabetic kidney disease: better than an angiotensin-converting enzyme inhibitor alone? | LitMetric

Angiotensin-(1-7) for diabetic kidney disease: better than an angiotensin-converting enzyme inhibitor alone?

Kidney Int

Department of Nephrology and Hypertension, Northwestern University, Chicago, Illinois, USA. Electronic address:

Published: October 2019

In this commentary we emphasize the renoprotective effect of cyclic angiotensin-(1-7) described by Cassis et al. in a mouse model of diabetic kidney disease. The importance of the study is that this peptide was even more protective than the angiotensin-converting enzyme inhibitor lisinopril administered alone and that when the 2 componds were combined, the renoprotective action was additive.

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http://dx.doi.org/10.1016/j.kint.2019.05.028DOI Listing

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