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Functional perfusion image guided radiation treatment planning for locally advanced lung cancer.

Phys Imaging Radiat Oncol

July 2019

Department of Radiation Oncology, Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney West Radiation Oncology Network, Hawksbury Road, Westmead, Sydney, NSW 2145, Australia.

Background And Purpose: Functional avoidance radiation therapy (RT) aims at sparing functional lung regions. The purpose of this simulation study was to evaluate the feasibility of functional lung avoidance methodology in RT of lung cancer and to characterize the achievable dosimetry of single photon emission computed tomography (SPECT) guided treatment planning.

Materials And Methods: Fifteen consecutive lung cancer patients were included and planned for definitive RT of 60-66 Gy in 2-Gy fractions.

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