Data are presented on 30 high and low incidence antigens and on the distribution of the alleles of 14 blood group systems in a random sample of Newfoundlanders. The distribution of alleles in Newfoundland was compared to founder populations where possible and to the Canadian Caucasian population in general; no significant differences were found. Six rare alleles were observed (IN*a, NFLD, TAR, RH*x, RH*w, RH*V) in a population of 234 individuals. A high incidence of rare alleles has been reported in other isolate populations.
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