AI Article Synopsis
- The study aimed to evaluate clinical, serological, biochemical, and hematological features in patients with hepatitis B (HBV) and Delta (HDV) viruses.
- Among the 112 patients analyzed, 74% were only infected with HBV, while 26% were co-infected with HDV; co-infected patients showed more symptoms and significant biochemical and hematologic changes.
- The findings indicate that co-infection with HDV is associated with a more severe clinical profile and greater liver disease progression compared to those with HBV alone.
Article Abstract
Objective: to analyze clinical, serological, biochemical and hematological aspects in patients infected with the hepatitis B (HBV) and Delta (HDV) viruses.
Method: cross-sectional, descriptive and retrospective study, performed with patients chronically infected with HBV and superinfected with HDV.
Results: among the 112 patients selected, 74% were monoinfected with HBV (Group HBV) and 26% were superinfected with HDV (Group HBV+HDV). There was no difference in gender distribution. The average age was 36 years with standard deviation of ±12 years. The symptoms and signs presented a higher proportion in Group HBV+HDV (p=0.001). In both groups, most patients had non-reactive AgHBe. The records of biochemical and hematologic changes showed highest proportion in Group VHB+VHD Group (p<0.05).
Conclusion: the study found that patients were in clinical stages of the disease different from those in the initial examination for monitoring their chronic condition. The clinical profile suggests greater severity of liver disease among the patients superinfected with HDV.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1590/0034-7167-2018-0100 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!