AI Article Synopsis
- - MINOCA (myocardial infarction with non-obstructive coronary arteries) refers to heart attacks where no significant blockages are found in the coronary arteries, but various underlying causes still contribute to the condition.
- - The causes of MINOCA can include less than 50% coronary artery blockage, plaque rupture, embolism, dissection, and spasms, requiring advanced diagnostic tools like cardiac imaging for accurate identification.
- - Contrary to earlier beliefs, the outlook for MINOCA patients is serious, with morbidity and mortality rates comparable to other heart attack types, highlighting the need for targeted treatment after determining the underlying cause.
Article Abstract
The term MINOCA (myocardial infarction with non-obstructive coronary arteries) defines acute myocardial infarction with angiographic evidence of no significant coronary artery stenosis. Heterogeneous diseases are labelled as MINOCA. Incidence and epidemiological aspects differ on the basis of etiological causes. MINOCA include plaque (causing <50% stenosis) rupture or erosion, coronary embolism and dissection, and coronary artery spasm. Diagnosis may require multiple diagnostic tools, including cardiac imaging or provocative tests, in addition to standard coronary angiography, according to clinical suspicion. Cardiac magnetic resonance plays a key role in confirming the diagnosis and excluding other diseases with similar clinical presentation. Prognosis is not as benign as previously thought, on the opposite it is characterized by morbidity and mortality rates similar to other forms of myocardial infarction. Once the causative mechanism has been identified, appropriate therapy can be delivered.
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| http://dx.doi.org/10.1714/3207.31839 | DOI Listing |
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