Naa10P puts a brake on PGC1α and fat browning.

Nat Struct Mol Biol

UCSF Diabetes Center, San Francisco, CA, USA.

Published: October 2019

Beige fat serves as a substantial metabolic sink that dissipates energy and has consequently attracted much attention as a target for improving metabolic health. A recent study has provided a new molecular target, the N-terminal acetyltransferase Naa10p, for harnessing beige-fat biogenesis and improving whole-body energy homeostasis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815931PMC
http://dx.doi.org/10.1038/s41594-019-0310-2DOI Listing

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