Hemolymph melanization is a conserved immune response in insects and other arthropods. However, the physiological process of the hemolymph system in the melanization response is hardly studied. Here, alterations of hemocytes in immune melanization were observed by infection in . Results first showed that there were cells aggregating into clusters. However, it vanished, and only part of clustered hemocytes were melanized during the period of intense immunity. The hemocyte numbers immediately decreased following an immune challenge, slowly increased to a peak, then reduced and finally returned to normalization. Granulocytes participated in cells aggregation at the early and later immune stage, while plasmatocytes were responsible for hemocytes agglomerate and melanization for the longest time, and more oenocytoids appeared at the peak stage of melanization. Moreover, hemocytes played a crucial role in resisting invasion of pathogens by agglomerate and melanization, and the circulatory system maintained higher hemocyte numbers and stronger antibacterial activity in fifth than fourth instar larvae after infection. In vitro immune melanization was most likely preferentially implemented in an independent process. These were the main characteristics reflecting the physiological process of hemolymph immune melanization, which provided an important foundation for further study of the complete mechanisms in the immunity of silkworm.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780253 | PMC |
| http://dx.doi.org/10.3390/insects10090301 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Encapsulation and Melanization Are Not Correlated to Successful Immune Defense Against Parasitoid Wasps in .
Cells
January 2025
Innate Immunity Group, Institute of Genetics, HUN-REN Biological Research Centre, 6726 Szeged, Hungary.
Parasitoid elimination in involves special hemocytes, called lamellocytes, which encapsulate the eggs or larvae of the parasitoid wasps. The capsules are melanized, and metabolites of the melanization reaction may play a potential role in parasitoid killing. We have observed a variation in the melanization capacity of different, commonly used strains, such as Canton-S, Oregon-R, and BL5905, BL6326.
View Article and Find Full Text PDFThe effect of population density on the phenotype, metabolic and immunological adaptations in the cuticle of Spodoptera litura larvae.
Pest Manag Sci
January 2025
Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, China.
Background: Species that experience outbreaks and those that display density-dependent phase polymorphism demonstrate density-dependent prophylaxis (DDP) by increasing their immune investment in response to increasing densities. Despite this phenomenon, the mechanisms of DDP remain largely unexplored.
Results: Here, we showed that Spodoptera litura exhibited heightened cuticular melanization and enhanced cuticular immune responses when reared at higher population density.
Laser-based selective killing of a manipulative parasite reveals partial reversibility of phenotypic alterations in its intermediate host.
Curr Res Parasitol Vector Borne Dis
October 2024
Laboratoire Interdisciplinaire Carnot de Bourgogne, UMR 6303 CNRS, Université Bourgogne Franche-Comté, 9 Avenue Alain Savary, 21078, Dijon, France.
Various parasites alter their intermediate host's phenotype in ways that increase parasite transmission to definitive hosts. To what extent infected intermediate hosts can recover from such "manipulation" is poorly documented, thus limiting our understanding of its proximate and ultimate causes. Here, we address the reversibility of several phenotypic alterations induced by the acanthocephalan , a trophically-transmitted bird parasite, in its amphipod intermediate host.
View Article and Find Full Text PDFThe synergistic potential of polyethylene glycol 400 for the control of Hyphantria cunea larvae by Beauveria bassiana.
Pestic Biochem Physiol
December 2024
School of Forestry, Northeast Forestry University, Harbin 150040, PR China; Key Laboratory of Sustainable Forest Ecosystem Management-Ministry of Education, Northeast Forestry University, Harbin 150040, PR China. Electronic address:
The efficacy of entomopathogenic fungi as pest control agents is constrained by both their physiological state and external environmental factors. This study identified synergists capable of enhancing the insecticidal activity of Beauveria bassiana (Bb) and investigated the underlying synergistic mechanisms. Our results found that among 6 potential synergists, polyethylene glycol 400 (PEG) and trehalose significantly improved Bb's lethality against Hyphantria cunea larvae, with PEG demonstrating the most pronounced effect.
View Article and Find Full Text PDFThe potential virulence of Listeria monocytogenes strains isolated from fresh produce processing facilities as determined by an invertebrate Galleria mellonella model.
PLoS One
December 2024
School of Applied Sciences, Edinburgh Napier University, Edinburgh, Scotland, United Kingdom.
Listeria monocytogenes, a bacterium responsible for listeriosis, is an environmental and food-borne pathogen that poses a particular risk to pregnant women and the elderly. While traditionally associated with animal products, ready-to-eat salads are increasingly recognised as a source of Listeria outbreaks. However, little is known about the potential virulence of Listeria isolates from the fresh produce environment.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!