AI Article Synopsis
- * Research indicates that miRNAs, particularly miR-186, are linked to cancer development and may vary in expression based on the type of cancer.
- * MiR-186 could potentially be used as a biomarker for diagnosing and predicting cancer outcomes, while its expression is influenced by various factors, underscoring its importance in cancer treatment strategies.
Article Abstract
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the post-transcriptional level. Mounting evidence suggests the involvement of miRNAs in carcinogenesis and the development of human cancer. Among the miRNAs, miR-186 has been extensively studied in various cancers. The expression of miR-186 in tissues varies depending on the type of cancer and miR-186 in tissues and body fluids may serve as a marker for the diagnosis and prognosis of cancers. Various biological processes in human cancer are affected by miR-186. Additionally, miR-186 itself is regulated by several factors. Thus, this evidence highlights the potential value of miR-186 in the diagnosis, prognosis and treatment of human cancer.
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| http://dx.doi.org/10.1016/j.biopha.2019.109428 | DOI Listing |
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