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Comparison of the efficacy and safety of Landiolol and Esmolol in critically ill patients: a propensity score-matched study.
Ann Intensive Care
January 2025
Service de Médecine Intensive-Réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Groupe de Recherche Clinique CARMAS, Université Paris-Saclay, AP-HP, Le Kremlin-Bicêtre, France.
Background: Excessive tachycardia is associated with impaired hemodynamics and worse outcome in critically ill patients. Previous studies suggested beneficial effect of β-blockers administration in ICU patients, including those with septic shock. However, comparisons in ICU settings are lacking.
View Article and Find Full Text PDFEvaluation of Enrichment Approaches for the Study of the Viromes in Mollusk Species.
Food Environ Virol
January 2025
Institute of Human Virology, Department of Pathogen Biology and Biosecurity, and Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Invasive alien species such as freshwater snails have significantly affected the food, environment, and the health of humans and animals, which have unfortunately received insufficient attention. To facilitate the study of viromes in snail species, we compared the enrichment effect of cesium chloride (CsCl) and sucrose density gradient ultracentrifugations in the recovery of diverse viruses in Pomacea canaliculata and Achatina fulica. First, we showed that CsCl-based ultracentrifugation enriched more virus contigs and reduced the nucleic acid background of the Pomacea canaliculata and was thus beneficial for virus recovery.
View Article and Find Full Text PDFRole of stomatal and leaf anatomical features in defining plant performance under elevated carbon dioxide and ozone, in the changing climate scenario.
Environ Sci Pollut Res Int
January 2025
Laboratory of Ecotoxicology, Department of Botany, Institute of Science, Banaras Hindu University, Varanasi, 221005, India.
This research investigates the interactive effects of elevated ozone (eO) and carbon dioxide (eCO) on stomatal morphology and leaf anatomical characteristics in two wheat cultivars with varying O sensitivities. Elevated O increased stomatal density and conductance, causing oxidative stress and cellular damage, particularly in the O-sensitive cultivar PBW-550 (PW), compared to HUW-55 (HW). Conversely, eCO reduced stomatal density and pore size, mitigating O-induced damage by limiting O influx.
View Article and Find Full Text PDFSusceptibility of different mice species to chemical induction of colorectal cancer by 1,2-dimethylhydrazine.
J Egypt Natl Canc Inst
January 2025
Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
Background: Colorectal cancer (CRC) is a major public health concern. Animal models play a crucial role in understanding the disease pathology and development of effective treatment strategies. Chemically induced CRC represents a cornerstone in animal model development; however, due to the presence of different animal species with different genetic backgrounds, it becomes mandatory to study the susceptibility of different mice species to CRC induction by different chemical entities such as 1,2-dimethylhydrazine (DMH).
View Article and Find Full Text PDFCurative-Intended Management of Synchronous Esophageal and Rectal Cancer-A Systematic Literature Review.
J Gastrointest Cancer
January 2025
Department of Radiotherapy and Radiation Oncology, Jena University Hospital, 07747, Jena, Germany.
Purpose: Synchronous esophageal (EC) and rectal carcinoma (RC) is a rare and challenging condition, particularly in curative-intended treatment. Especially locally advanced tumors may not be suitable for primary resection and require individual multimodal treatment. This review examines curative-intended management of synchronous EC and RC.
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