Myelomatous pleural effusion (MPE) is a rare complication in patients suffering from multiple myeloma (MM). Dyspnea is the predominant symptom in the clinical presentation. Poor prognosis and aggressive MM behavior have been linked to this condition. We describe a case of MPE in an undiagnosed MM patient who presented with respiratory discomfort and general malaise.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741372PMC
http://dx.doi.org/10.7759/cureus.5153DOI Listing

Publication Analysis

Top Keywords

myelomatous pleural
8
pleural effusion
8
effusion presenting
4
presenting symptom
4
symptom case
4
case report
4
report myelomatous
4
effusion mpe
4
mpe rare
4
rare complication
4

Similar Publications

Myelomatous pleural effusion (MPE) is a rare, often treatment-resistant complication of multiple myeloma. Intrapleural bortezomib shows promise but lacks standardized dosing. We report a 62-year-old woman with MPE treated with 1.

View Article and Find Full Text PDF

Multiple myeloma is a rare haematological malignancy characterised by the clonal proliferation of plasma cells within the bone marrow. Typical manifestations include bone pain, fatigue and monoclonal protein elevation in serum and urine. Less than 1% of cases develop myelomatous pleural effusion, a severe complication indicative of advanced disease and a very poor prognosis.

View Article and Find Full Text PDF

Multiple myeloma is a common malignant bone-based disease. Pleural effusions reported in these patients remain rare. It is commonly due to congestive heart disease, pulmonary embolism, nephrotic syndrome or a second neoplasia.

View Article and Find Full Text PDF

Myelomatous pleural effusion in multiple myeloma- A rare presentation.

J Cancer Res Ther

January 2024

Department of Pathology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India.

Article Synopsis
  • * A case report highlights a 41-year-old patient experiencing bilateral pleural effusion during a relapse of multiple myeloma, treated with a chemotherapy regimen that included cyclophosphamide, bortezomib, and dexamethasone.
  • * Despite an initial positive response to treatment, the patient's condition deteriorated, leading to a poor prognosis and eventual death, underscoring the need for early diagnosis and treatment to potentially enhance outcomes in similar cases.
View Article and Find Full Text PDF

Multiple myeloma (MM) is a hematologic malignancy characterized by the clonal proliferation of plasma cells in the bone marrow. It commonly presents with bone pain, anemia, renal failure, and hypercalcemia. Pleural effusion in MM usually has multiple causes, but it is rare for the effusion to be due to myelomatous deposition of the pleura.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!