AI Article Synopsis
- - A four-year-old child suffered from cardiac conduction issues, specifically reversible sinoatrial block, after taking a toxic dose of carbamazepine, despite having a serum level near the therapeutic limit.
- - The case highlights a lack of previous reports on sinoatrial block due to acute carbamazepine poisoning in children, even though it has been observed in adults at therapeutic doses.
- - The study emphasizes the importance of using electrocardiograms to evaluate and monitor pediatric patients who experience acute poisoning with carbamazepine.
Article Abstract
Cardiac conduction abnormalities are reported after ingestion of a toxic dose of carbamazepine. We describe the case of a four-year-old child with carbamazepine acute poisoning who developed reversible synoatrial block along with neurological toxic signs, despite a serum level of carbamazepine close to the upper limit of the therapeutic range. Although carbamazepine-induced sinoatrial block has been reported in the literature even at therapeutic doses in adult patients, our personal research has not identified any record of this cardiac conduction abnormality in acute carbamazepine poisoning at pediatric age. The electrocardiogram is indispensable in the assessment and monitoring of pediatric cases with acute poisoning with carbamazepine.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709395 | PMC |
| http://dx.doi.org/10.26574/maedica.2019.14.2.165 | DOI Listing |
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