BACKGROUND Ecthyma gangrenosum is an uncommon cutaneous infection commonly caused by Pseudomonas aeruginosa affecting typically immunocompromised patients. The presence of ecthyma gangrenosum can be associated with severe systemic infection often with a fatal prognosis. Most cases of ecthyma gangrenosum occur around the axilla, buttocks, and limbs; the scrotum is rarely affected. CASE REPORT A 68-year-old male with previously diagnosed acute myeloid leukemia, presented with left scrotal pain, fever, and rigors. Physical examination showed 2 ulcerating lesions with central black eschars surrounded by erythematous halos on the superior aspect of the left scrotum. Diagnosis of ecthyma gangrenosum was confirmed as both blood and lesion cultures showed growth of P. aeruginosa. After early empiric antibiotic treatment, the lesions significantly improved, and no sign of recurrence or new lesions was noticed. CONCLUSIONS Ecthyma gangrenosum should be considered in the differential diagnosis of ulcerating lesions of the scrotum. An early diagnosis and aggressive antibiotic treatment are imperative for resolution of this infection.
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http://dx.doi.org/10.12659/AJCR.917443 | DOI Listing |
Rev Med Chil
July 2024
Resident Department of Dermatology, Faculty of Medicine, University of Chile, Santiago, Chile.
This report describes the case of a 64-year-old female patient, with multiple comorbidities which presented an ecthyma gangrenosum due to Klebsiella pneumoniae confirmed by blood and tissue cultures. It finally ended in the amputation of the limb. The case is presented given the low prevalence of positive cultures for this microorganism in this pathology associated to devastating consequences for the patient.
View Article and Find Full Text PDFMayo Clin Proc
January 2025
Department of Dermatology, Mayo Clinic, Rochester, MN.
Dermatol Pract Concept
October 2024
Department of Geriatric - wound and healing, Rothschild Hospital, Sorbonne University, Paris, France.
J Ayub Med Coll Abbottabad
November 2024
Ziauddin Hospital KDLB, Karachi-Pakistan.
Ecthyma gangrenosum is a rare and severe skin disease that is typically accompanied by a systemic infection caused by Pseudomonas aeruginosa bacteria. It manifests as painful, necrotic lesions surrounded by redness and including a noticeable black eschar in the centre. The majority of ecthyma gangrenosum instances occur in immunocompromised individuals, such as those with significant underlying medical conditions or those who are neutropenic.
View Article and Find Full Text PDFCase Rep Dermatol
November 2024
Microbiology Program, School of Basic Sciences, Universidad Santiago de Cali, Cali, Colombia.
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